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From systems to structure — using genetic data to model protein structures

Understanding the effects of genetic variation is a fundamental problem in biology that requires methods to analyse both physical and functional consequences of sequence changes at systems-wide and mechanistic scales. To achieve a systems view, protein interaction networks map which proteins physica...

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Detalles Bibliográficos
Autores principales: Braberg, Hannes, Echeverria, Ignacia, Kaake, Robyn M., Sali, Andrej, Krogan, Nevan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744059/
https://www.ncbi.nlm.nih.gov/pubmed/35013567
http://dx.doi.org/10.1038/s41576-021-00441-w

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