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From systems to structure — using genetic data to model protein structures
Understanding the effects of genetic variation is a fundamental problem in biology that requires methods to analyse both physical and functional consequences of sequence changes at systems-wide and mechanistic scales. To achieve a systems view, protein interaction networks map which proteins physica...
Autores principales: | Braberg, Hannes, Echeverria, Ignacia, Kaake, Robyn M., Sali, Andrej, Krogan, Nevan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744059/ https://www.ncbi.nlm.nih.gov/pubmed/35013567 http://dx.doi.org/10.1038/s41576-021-00441-w |
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