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Practical Risk Scoring System for Predicting Severity of COVID-19 Disease

OBJECTIVES: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19 disease, has become an international pandemic with numerous casualties. It had been noted that the severity of the COVID-19 disease course depends on several clinical, laboratory, and radiologic...

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Autores principales: Petersen, Jeffrey, Jhala, Darshana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744169/
https://www.ncbi.nlm.nih.gov/pubmed/35024610
http://dx.doi.org/10.1177/2632010X211068427
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author Petersen, Jeffrey
Jhala, Darshana
author_facet Petersen, Jeffrey
Jhala, Darshana
author_sort Petersen, Jeffrey
collection PubMed
description OBJECTIVES: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19 disease, has become an international pandemic with numerous casualties. It had been noted that the severity of the COVID-19 disease course depends on several clinical, laboratory, and radiological factors. This has led to risk scoring systems in various populations such as in China, but similar risk scoring systems based on the American veteran population are sparse, particularly with the vulnerable Veteran population. As a simple risk scoring system would be very useful, we propose a simple Jhala Risk Scoring System (JRSS) to assess the severity of disease risk. METHODS: A retrospective review of all SARS-CoV-2 reverse transcriptase-polymerase chain reaction (RT-PCR) tests collected and performed at the regional Veterans Administration Medical Center (VAMC) serving the Philadelphia and surrounding areas from March 17th, 2020 to May 20th, 2020. Data was collected and analyzed in the same year. These tests were reviewed within the computerized medical record system for demographic, medical history, laboratory test history, and clinical course. Information from the medical records were then scored based on the criteria of the Jhala Risk Scoring System (JRSS). RESULTS: The JRSS, based on age, ethnicity, presence of any lung disease, presence of cardiovascular disease, smoking history, and diabetes history with laboratory parameters correlated and predicted (with statistical significance) which patients would be hospitalized. CONCLUSION: The JRSS may play a role in informing which COVID-19 positive patients in the emergency room/urgent care for risk stratification.
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spelling pubmed-87441692022-01-11 Practical Risk Scoring System for Predicting Severity of COVID-19 Disease Petersen, Jeffrey Jhala, Darshana Clin Pathol Original Research OBJECTIVES: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19 disease, has become an international pandemic with numerous casualties. It had been noted that the severity of the COVID-19 disease course depends on several clinical, laboratory, and radiological factors. This has led to risk scoring systems in various populations such as in China, but similar risk scoring systems based on the American veteran population are sparse, particularly with the vulnerable Veteran population. As a simple risk scoring system would be very useful, we propose a simple Jhala Risk Scoring System (JRSS) to assess the severity of disease risk. METHODS: A retrospective review of all SARS-CoV-2 reverse transcriptase-polymerase chain reaction (RT-PCR) tests collected and performed at the regional Veterans Administration Medical Center (VAMC) serving the Philadelphia and surrounding areas from March 17th, 2020 to May 20th, 2020. Data was collected and analyzed in the same year. These tests were reviewed within the computerized medical record system for demographic, medical history, laboratory test history, and clinical course. Information from the medical records were then scored based on the criteria of the Jhala Risk Scoring System (JRSS). RESULTS: The JRSS, based on age, ethnicity, presence of any lung disease, presence of cardiovascular disease, smoking history, and diabetes history with laboratory parameters correlated and predicted (with statistical significance) which patients would be hospitalized. CONCLUSION: The JRSS may play a role in informing which COVID-19 positive patients in the emergency room/urgent care for risk stratification. SAGE Publications 2022-01-07 /pmc/articles/PMC8744169/ /pubmed/35024610 http://dx.doi.org/10.1177/2632010X211068427 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research
Petersen, Jeffrey
Jhala, Darshana
Practical Risk Scoring System for Predicting Severity of COVID-19 Disease
title Practical Risk Scoring System for Predicting Severity of COVID-19 Disease
title_full Practical Risk Scoring System for Predicting Severity of COVID-19 Disease
title_fullStr Practical Risk Scoring System for Predicting Severity of COVID-19 Disease
title_full_unstemmed Practical Risk Scoring System for Predicting Severity of COVID-19 Disease
title_short Practical Risk Scoring System for Predicting Severity of COVID-19 Disease
title_sort practical risk scoring system for predicting severity of covid-19 disease
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744169/
https://www.ncbi.nlm.nih.gov/pubmed/35024610
http://dx.doi.org/10.1177/2632010X211068427
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