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Monocarboxylate transporter functions and neuroprotective effects of valproic acid in experimental models of amyotrophic lateral sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a devasting neurodegenerative disorder for which no successful therapeutics are available. Valproic acid (VPA), a monocarboxylate derivative, is a known antiepileptic drug and a histone deacetylase inhibitor. METHODS: To investigate whether monocarb...

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Detalles Bibliográficos
Autores principales:	Gyawali, Asmita, Latif, Sana, Choi, Seung-Hye, Hyeon, Seung Jae, Ryu, Hoon, Kang, Young-Sook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744235/ https://www.ncbi.nlm.nih.gov/pubmed/35012534 http://dx.doi.org/10.1186/s12929-022-00785-3

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