In vitro response of THP-1 derived macrophages to antimicrobially effective PHMB-coated Ti6Al4V alloy implant material with and without contamination with S. epidermidis and P. aeruginosa

AIM: Periprosthetic joint infections are a devastating complication after arthroplasty, leading to rejection of the prosthesis. The prevention of septic loosening may be possible by an antimicrobial coating of the implant surface. Poly (hexamethylene) biguanide hydrochloride [PHMB] seems to be a sui...

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Detalles Bibliográficos
Autores principales: Zwicker, Paula, Schmidt, Thomas, Hornschuh, Melanie, Lode, Holger, Kramer, Axel, Müller, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744236/
https://www.ncbi.nlm.nih.gov/pubmed/35000621
http://dx.doi.org/10.1186/s40824-021-00247-1

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