Optical genome mapping identifies rare structural variations as predisposition factors associated with severe COVID-19

Impressive global efforts have identified both rare and common gene variants associated with severe COVID-19 using sequencing technologies. However, these studies lack the sensitivity to accurately detect several classes of variants, especially large structural variants (SVs), which account for a su...

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Detalles Bibliográficos
Autores principales: Sahajpal, Nikhil Shri, Jill Lai, Chi-Yu, Hastie, Alex, Mondal, Ashis K., Dehkordi, Siavash Raeisi, van der Made, Caspar I., Fedrigo, Olivier, Al-Ajli, Farooq, Jalnapurkar, Sawan, Byrska-Bishop, Marta, Kanagal-Shamanna, Rashmi, Levy, Brynn, Schieck, Maximilian, Illig, Thomas, Bacanu, Silviu-Alin, Chou, Janet S., Randolph, Adrienne G., Rojiani, Amyn M., Zody, Michael C., Brownstein, Catherine A., Beggs, Alan H., Bafna, Vineet, Jarvis, Erich D., Hoischen, Alexander, Chaubey, Alka, Kolhe, Ravindra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744399/
https://www.ncbi.nlm.nih.gov/pubmed/35036860
http://dx.doi.org/10.1016/j.isci.2022.103760

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