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Cutaneous Crohn Disease without Intestinal Manifestations

Extraintestinal manifestations (EIMs) are common in patients with Crohn's disease (CD). Various reactive cutaneous conditions, including erythema nodosum and pyoderma gangrenosum frequently occur as a part of EIMs. However, cutaneous metastasis of CD is rarely encountered in CD patients. Here,...

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Autores principales: Vahabi-Amlashi, Sadegh, Molkara, Sara, Shahrokhi, Yahya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744419/
https://www.ncbi.nlm.nih.gov/pubmed/35071107
http://dx.doi.org/10.4103/abr.abr_180_19
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author Vahabi-Amlashi, Sadegh
Molkara, Sara
Shahrokhi, Yahya
author_facet Vahabi-Amlashi, Sadegh
Molkara, Sara
Shahrokhi, Yahya
author_sort Vahabi-Amlashi, Sadegh
collection PubMed
description Extraintestinal manifestations (EIMs) are common in patients with Crohn's disease (CD). Various reactive cutaneous conditions, including erythema nodosum and pyoderma gangrenosum frequently occur as a part of EIMs. However, cutaneous metastasis of CD is rarely encountered in CD patients. Here, we report a 28-year-old female patient presenting with discharging deep fissures on genital and intergluteal regions. The result of a skin biopsy showed noncaseating granulomas. After rule out all the other differential diagnoses for granulomatous skin lesions, we believe this patient may be a case of CD, presenting with skin metastasis and GI tract involvement has not been occurred during 1-year follow-up. We suggest including cutaneous (metastatic) CD in the list of dermatologic differential diagnoses for cutaneous lesions of these sites. These lesions can occasionally precede gastrointestinal (GI) involvement by months and years, therefore, an appropriate follow-up needs to be done to detect GI lesions as soon as they appear.
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spelling pubmed-87444192022-01-21 Cutaneous Crohn Disease without Intestinal Manifestations Vahabi-Amlashi, Sadegh Molkara, Sara Shahrokhi, Yahya Adv Biomed Res Case Report Extraintestinal manifestations (EIMs) are common in patients with Crohn's disease (CD). Various reactive cutaneous conditions, including erythema nodosum and pyoderma gangrenosum frequently occur as a part of EIMs. However, cutaneous metastasis of CD is rarely encountered in CD patients. Here, we report a 28-year-old female patient presenting with discharging deep fissures on genital and intergluteal regions. The result of a skin biopsy showed noncaseating granulomas. After rule out all the other differential diagnoses for granulomatous skin lesions, we believe this patient may be a case of CD, presenting with skin metastasis and GI tract involvement has not been occurred during 1-year follow-up. We suggest including cutaneous (metastatic) CD in the list of dermatologic differential diagnoses for cutaneous lesions of these sites. These lesions can occasionally precede gastrointestinal (GI) involvement by months and years, therefore, an appropriate follow-up needs to be done to detect GI lesions as soon as they appear. Wolters Kluwer - Medknow 2021-11-26 /pmc/articles/PMC8744419/ /pubmed/35071107 http://dx.doi.org/10.4103/abr.abr_180_19 Text en Copyright: © 2021 Advanced Biomedical Research https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Vahabi-Amlashi, Sadegh
Molkara, Sara
Shahrokhi, Yahya
Cutaneous Crohn Disease without Intestinal Manifestations
title Cutaneous Crohn Disease without Intestinal Manifestations
title_full Cutaneous Crohn Disease without Intestinal Manifestations
title_fullStr Cutaneous Crohn Disease without Intestinal Manifestations
title_full_unstemmed Cutaneous Crohn Disease without Intestinal Manifestations
title_short Cutaneous Crohn Disease without Intestinal Manifestations
title_sort cutaneous crohn disease without intestinal manifestations
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744419/
https://www.ncbi.nlm.nih.gov/pubmed/35071107
http://dx.doi.org/10.4103/abr.abr_180_19
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