Cargando…
Cutaneous Crohn Disease without Intestinal Manifestations
Extraintestinal manifestations (EIMs) are common in patients with Crohn's disease (CD). Various reactive cutaneous conditions, including erythema nodosum and pyoderma gangrenosum frequently occur as a part of EIMs. However, cutaneous metastasis of CD is rarely encountered in CD patients. Here,...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744419/ https://www.ncbi.nlm.nih.gov/pubmed/35071107 http://dx.doi.org/10.4103/abr.abr_180_19 |
_version_ | 1784630115025551360 |
---|---|
author | Vahabi-Amlashi, Sadegh Molkara, Sara Shahrokhi, Yahya |
author_facet | Vahabi-Amlashi, Sadegh Molkara, Sara Shahrokhi, Yahya |
author_sort | Vahabi-Amlashi, Sadegh |
collection | PubMed |
description | Extraintestinal manifestations (EIMs) are common in patients with Crohn's disease (CD). Various reactive cutaneous conditions, including erythema nodosum and pyoderma gangrenosum frequently occur as a part of EIMs. However, cutaneous metastasis of CD is rarely encountered in CD patients. Here, we report a 28-year-old female patient presenting with discharging deep fissures on genital and intergluteal regions. The result of a skin biopsy showed noncaseating granulomas. After rule out all the other differential diagnoses for granulomatous skin lesions, we believe this patient may be a case of CD, presenting with skin metastasis and GI tract involvement has not been occurred during 1-year follow-up. We suggest including cutaneous (metastatic) CD in the list of dermatologic differential diagnoses for cutaneous lesions of these sites. These lesions can occasionally precede gastrointestinal (GI) involvement by months and years, therefore, an appropriate follow-up needs to be done to detect GI lesions as soon as they appear. |
format | Online Article Text |
id | pubmed-8744419 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-87444192022-01-21 Cutaneous Crohn Disease without Intestinal Manifestations Vahabi-Amlashi, Sadegh Molkara, Sara Shahrokhi, Yahya Adv Biomed Res Case Report Extraintestinal manifestations (EIMs) are common in patients with Crohn's disease (CD). Various reactive cutaneous conditions, including erythema nodosum and pyoderma gangrenosum frequently occur as a part of EIMs. However, cutaneous metastasis of CD is rarely encountered in CD patients. Here, we report a 28-year-old female patient presenting with discharging deep fissures on genital and intergluteal regions. The result of a skin biopsy showed noncaseating granulomas. After rule out all the other differential diagnoses for granulomatous skin lesions, we believe this patient may be a case of CD, presenting with skin metastasis and GI tract involvement has not been occurred during 1-year follow-up. We suggest including cutaneous (metastatic) CD in the list of dermatologic differential diagnoses for cutaneous lesions of these sites. These lesions can occasionally precede gastrointestinal (GI) involvement by months and years, therefore, an appropriate follow-up needs to be done to detect GI lesions as soon as they appear. Wolters Kluwer - Medknow 2021-11-26 /pmc/articles/PMC8744419/ /pubmed/35071107 http://dx.doi.org/10.4103/abr.abr_180_19 Text en Copyright: © 2021 Advanced Biomedical Research https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Vahabi-Amlashi, Sadegh Molkara, Sara Shahrokhi, Yahya Cutaneous Crohn Disease without Intestinal Manifestations |
title | Cutaneous Crohn Disease without Intestinal Manifestations |
title_full | Cutaneous Crohn Disease without Intestinal Manifestations |
title_fullStr | Cutaneous Crohn Disease without Intestinal Manifestations |
title_full_unstemmed | Cutaneous Crohn Disease without Intestinal Manifestations |
title_short | Cutaneous Crohn Disease without Intestinal Manifestations |
title_sort | cutaneous crohn disease without intestinal manifestations |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744419/ https://www.ncbi.nlm.nih.gov/pubmed/35071107 http://dx.doi.org/10.4103/abr.abr_180_19 |
work_keys_str_mv | AT vahabiamlashisadegh cutaneouscrohndiseasewithoutintestinalmanifestations AT molkarasara cutaneouscrohndiseasewithoutintestinalmanifestations AT shahrokhiyahya cutaneouscrohndiseasewithoutintestinalmanifestations |