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Androgen Effects on Neural Plasticity
Androgens are synthesized in the brain, gonads, and adrenal glands, in both sexes, exerting physiologically important effects on the structure and function of the central nervous system. These effects may contribute to the incidence and progression of neurological disorders such as autism spectrum d...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744448/ https://www.ncbi.nlm.nih.gov/pubmed/35024693 http://dx.doi.org/10.1089/andro.2021.0022 |
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author | Kuwahara, Nariko Nicholson, Kate Isaacs, Lauren MacLusky, Neil J. |
author_facet | Kuwahara, Nariko Nicholson, Kate Isaacs, Lauren MacLusky, Neil J. |
author_sort | Kuwahara, Nariko |
collection | PubMed |
description | Androgens are synthesized in the brain, gonads, and adrenal glands, in both sexes, exerting physiologically important effects on the structure and function of the central nervous system. These effects may contribute to the incidence and progression of neurological disorders such as autism spectrum disorder, schizophrenia, and Alzheimer's disease, which occur at different rates in males and females. This review briefly summarizes the current state of knowledge with respect to the neuroplastic effects of androgens, with particular emphasis on the hippocampus, which has been the focus of much of the research in this field. |
format | Online Article Text |
id | pubmed-8744448 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Mary Ann Liebert, Inc., publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-87444482022-01-10 Androgen Effects on Neural Plasticity Kuwahara, Nariko Nicholson, Kate Isaacs, Lauren MacLusky, Neil J. Androg Clin Res Ther Androgens and the Nervous System: Review Androgens are synthesized in the brain, gonads, and adrenal glands, in both sexes, exerting physiologically important effects on the structure and function of the central nervous system. These effects may contribute to the incidence and progression of neurological disorders such as autism spectrum disorder, schizophrenia, and Alzheimer's disease, which occur at different rates in males and females. This review briefly summarizes the current state of knowledge with respect to the neuroplastic effects of androgens, with particular emphasis on the hippocampus, which has been the focus of much of the research in this field. Mary Ann Liebert, Inc., publishers 2021-12-23 /pmc/articles/PMC8744448/ /pubmed/35024693 http://dx.doi.org/10.1089/andro.2021.0022 Text en © Nariko Kuwahara et al., 2021; Published by Mary Ann Liebert, Inc. https://creativecommons.org/licenses/by/4.0/This Open Access article is distributed under the terms of the Creative Commons License [CC-BY] (http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Androgens and the Nervous System: Review Kuwahara, Nariko Nicholson, Kate Isaacs, Lauren MacLusky, Neil J. Androgen Effects on Neural Plasticity |
title | Androgen Effects on Neural Plasticity |
title_full | Androgen Effects on Neural Plasticity |
title_fullStr | Androgen Effects on Neural Plasticity |
title_full_unstemmed | Androgen Effects on Neural Plasticity |
title_short | Androgen Effects on Neural Plasticity |
title_sort | androgen effects on neural plasticity |
topic | Androgens and the Nervous System: Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744448/ https://www.ncbi.nlm.nih.gov/pubmed/35024693 http://dx.doi.org/10.1089/andro.2021.0022 |
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