Peptide stapling by late-stage Suzuki–Miyaura cross-coupling

The development of peptide stapling techniques to stabilise α-helical secondary structure motifs of peptides led to the design of modulators of protein–protein interactions, which had been considered undruggable for a long time. We disclose a novel approach towards peptide stapling utilising macrocy...

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Detalles Bibliográficos
Autores principales: Gruß, Hendrik, Feiner, Rebecca C, Mseya, Ridhiwan, Schröder, David C, Jewgiński, Michał, Müller, Kristian M, Latajka, Rafał, Marion, Antoine, Sewald, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744458/
https://www.ncbi.nlm.nih.gov/pubmed/35047078
http://dx.doi.org/10.3762/bjoc.18.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744458/
https://www.ncbi.nlm.nih.gov/pubmed/35047078
http://dx.doi.org/10.3762/bjoc.18.1

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