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1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis
Several low molecular weight naphthoquinones are very useful in organic synthesis. These compounds have given rise to thousands of other naphthoquinones that have been tested against various microorganisms and pharmacological targets, including being used in the preparation of several drugs that are...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Beilstein-Institut
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744465/ https://www.ncbi.nlm.nih.gov/pubmed/35047082 http://dx.doi.org/10.3762/bjoc.18.5 |
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author | Ribeiro, Ruan Carlos B Ferreira, Patricia G Borges, Amanda de A Forezi, Luana da S M da Silva, Fernando de Carvalho Ferreira, Vitor F |
author_facet | Ribeiro, Ruan Carlos B Ferreira, Patricia G Borges, Amanda de A Forezi, Luana da S M da Silva, Fernando de Carvalho Ferreira, Vitor F |
author_sort | Ribeiro, Ruan Carlos B |
collection | PubMed |
description | Several low molecular weight naphthoquinones are very useful in organic synthesis. These compounds have given rise to thousands of other naphthoquinones that have been tested against various microorganisms and pharmacological targets, including being used in the preparation of several drugs that are on the pharmaceutical market. Among these naphthoquinones, the series of compounds prepared from 1,2-naphthoquinone-4-sulfonic acid salts (β-NQS) stands out. In addition to being used in organic synthesis, they are excellent analytical derivatization reagents to spectrophotometrically determine drugs containing primary and secondary amino groups. This review summarizes the literature involving β-NQS. |
format | Online Article Text |
id | pubmed-8744465 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Beilstein-Institut |
record_format | MEDLINE/PubMed |
spelling | pubmed-87444652022-01-18 1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis Ribeiro, Ruan Carlos B Ferreira, Patricia G Borges, Amanda de A Forezi, Luana da S M da Silva, Fernando de Carvalho Ferreira, Vitor F Beilstein J Org Chem Review Several low molecular weight naphthoquinones are very useful in organic synthesis. These compounds have given rise to thousands of other naphthoquinones that have been tested against various microorganisms and pharmacological targets, including being used in the preparation of several drugs that are on the pharmaceutical market. Among these naphthoquinones, the series of compounds prepared from 1,2-naphthoquinone-4-sulfonic acid salts (β-NQS) stands out. In addition to being used in organic synthesis, they are excellent analytical derivatization reagents to spectrophotometrically determine drugs containing primary and secondary amino groups. This review summarizes the literature involving β-NQS. Beilstein-Institut 2022-01-05 /pmc/articles/PMC8744465/ /pubmed/35047082 http://dx.doi.org/10.3762/bjoc.18.5 Text en Copyright © 2022, Ribeiro et al. https://creativecommons.org/licenses/by/4.0/This is an open access article licensed under the terms of the Beilstein-Institut Open Access License Agreement (https://www.beilstein-journals.org/bjoc/terms/terms), which is identical to the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ). The reuse of material under this license requires that the author(s), source and license are credited. Third-party material in this article could be subject to other licenses (typically indicated in the credit line), and in this case, users are required to obtain permission from the license holder to reuse the material. |
spellingShingle | Review Ribeiro, Ruan Carlos B Ferreira, Patricia G Borges, Amanda de A Forezi, Luana da S M da Silva, Fernando de Carvalho Ferreira, Vitor F 1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis |
title | 1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis |
title_full | 1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis |
title_fullStr | 1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis |
title_full_unstemmed | 1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis |
title_short | 1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis |
title_sort | 1,2-naphthoquinone-4-sulfonic acid salts in organic synthesis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744465/ https://www.ncbi.nlm.nih.gov/pubmed/35047082 http://dx.doi.org/10.3762/bjoc.18.5 |
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