Diverse tumorigenic consequences of human papillomavirus integration in primary oropharyngeal cancers

Human papillomavirus (HPV) causes 5% of all cancers and frequently integrates into host chromosomes. The HPV oncoproteins E6 and E7 are necessary but insufficient for cancer formation, indicating that additional secondary genetic events are required. Here, we investigate potential oncogenic impacts...

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Detalles Bibliográficos
Autores principales: Symer, David E., Akagi, Keiko, Geiger, Heather M., Song, Yang, Li, Gaiyun, Emde, Anne-Katrin, Xiao, Weihong, Jiang, Bo, Corvelo, André, Toussaint, Nora C., Li, Jingfeng, Agrawal, Amit, Ozer, Enver, El-Naggar, Adel K., Du, Zoe, Shewale, Jitesh B., Stache-Crain, Birgit, Zucker, Mark, Robine, Nicolas, Coombes, Kevin R., Gillison, Maura L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744672/
https://www.ncbi.nlm.nih.gov/pubmed/34903527
http://dx.doi.org/10.1101/gr.275911.121

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