Cargando…

Morbidity, Clinical Course and Vaccination against SARS-CoV-2 Virus in Patients with Duchenne Muscular Dystrophy: A Patient Reported Survey

Background: Patients with Duchenne muscular dystrophy (DMD) may be at higher risk of a severe course of COVID-19. The aim of the study was to evaluate: (1) the incidence and course of COVID-19 infection in DMD patients; (2) the vaccination status of DMD patients; and (3) COVID-19 related anxiety amo...

Descripción completa

Detalles Bibliográficos
Autores principales: Wasilewska, Eliza, Sobierajska-Rek, Agnieszka, Śledzińska, Karolina, Małgorzewicz, Sylwia, Jassem, Ewa, Wierzba, Jolanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744807/
https://www.ncbi.nlm.nih.gov/pubmed/35010666
http://dx.doi.org/10.3390/ijerph19010406
_version_ 1784630197679554560
author Wasilewska, Eliza
Sobierajska-Rek, Agnieszka
Śledzińska, Karolina
Małgorzewicz, Sylwia
Jassem, Ewa
Wierzba, Jolanta
author_facet Wasilewska, Eliza
Sobierajska-Rek, Agnieszka
Śledzińska, Karolina
Małgorzewicz, Sylwia
Jassem, Ewa
Wierzba, Jolanta
author_sort Wasilewska, Eliza
collection PubMed
description Background: Patients with Duchenne muscular dystrophy (DMD) may be at higher risk of a severe course of COVID-19. The aim of the study was to evaluate: (1) the incidence and course of COVID-19 infection in DMD patients; (2) the vaccination status of DMD patients; and (3) COVID-19 related anxiety among DMD families. Materials and Methods: The study was conducted during an online symposium for DMD patients and their families. All participants (DMD families; n = 150) were asked to fill in the online survey with questions about COVID-19 infection history, vaccination against SARS-CoV-2 and anxiety during pandemic. Results: 53 DMD patients filled in the survey. Five (9.43%) were COVID-19 positive with mild symptoms of respiratory infection and anosmia; 23 (42.6%) were vaccinated, but in almost 20% of DMD families, none of the family members was vaccinated. Respondents revealed anxiety related both to the vaccination procedure and to COVID-19 infection (complications after infection 93.6%, death 62.4% respondents). Changes in health care system organization also aroused concern among participants (85.3%). Conclusion: The course of the COVID-19 infection in DMD patients was mild. Not enough patients with DMD and their families are vaccinated. Education about the management of COVID-19 infections and the vaccination procedure for DMD patients is needed and expected.
format Online
Article
Text
id pubmed-8744807
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-87448072022-01-11 Morbidity, Clinical Course and Vaccination against SARS-CoV-2 Virus in Patients with Duchenne Muscular Dystrophy: A Patient Reported Survey Wasilewska, Eliza Sobierajska-Rek, Agnieszka Śledzińska, Karolina Małgorzewicz, Sylwia Jassem, Ewa Wierzba, Jolanta Int J Environ Res Public Health Article Background: Patients with Duchenne muscular dystrophy (DMD) may be at higher risk of a severe course of COVID-19. The aim of the study was to evaluate: (1) the incidence and course of COVID-19 infection in DMD patients; (2) the vaccination status of DMD patients; and (3) COVID-19 related anxiety among DMD families. Materials and Methods: The study was conducted during an online symposium for DMD patients and their families. All participants (DMD families; n = 150) were asked to fill in the online survey with questions about COVID-19 infection history, vaccination against SARS-CoV-2 and anxiety during pandemic. Results: 53 DMD patients filled in the survey. Five (9.43%) were COVID-19 positive with mild symptoms of respiratory infection and anosmia; 23 (42.6%) were vaccinated, but in almost 20% of DMD families, none of the family members was vaccinated. Respondents revealed anxiety related both to the vaccination procedure and to COVID-19 infection (complications after infection 93.6%, death 62.4% respondents). Changes in health care system organization also aroused concern among participants (85.3%). Conclusion: The course of the COVID-19 infection in DMD patients was mild. Not enough patients with DMD and their families are vaccinated. Education about the management of COVID-19 infections and the vaccination procedure for DMD patients is needed and expected. MDPI 2021-12-30 /pmc/articles/PMC8744807/ /pubmed/35010666 http://dx.doi.org/10.3390/ijerph19010406 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wasilewska, Eliza
Sobierajska-Rek, Agnieszka
Śledzińska, Karolina
Małgorzewicz, Sylwia
Jassem, Ewa
Wierzba, Jolanta
Morbidity, Clinical Course and Vaccination against SARS-CoV-2 Virus in Patients with Duchenne Muscular Dystrophy: A Patient Reported Survey
title Morbidity, Clinical Course and Vaccination against SARS-CoV-2 Virus in Patients with Duchenne Muscular Dystrophy: A Patient Reported Survey
title_full Morbidity, Clinical Course and Vaccination against SARS-CoV-2 Virus in Patients with Duchenne Muscular Dystrophy: A Patient Reported Survey
title_fullStr Morbidity, Clinical Course and Vaccination against SARS-CoV-2 Virus in Patients with Duchenne Muscular Dystrophy: A Patient Reported Survey
title_full_unstemmed Morbidity, Clinical Course and Vaccination against SARS-CoV-2 Virus in Patients with Duchenne Muscular Dystrophy: A Patient Reported Survey
title_short Morbidity, Clinical Course and Vaccination against SARS-CoV-2 Virus in Patients with Duchenne Muscular Dystrophy: A Patient Reported Survey
title_sort morbidity, clinical course and vaccination against sars-cov-2 virus in patients with duchenne muscular dystrophy: a patient reported survey
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744807/
https://www.ncbi.nlm.nih.gov/pubmed/35010666
http://dx.doi.org/10.3390/ijerph19010406
work_keys_str_mv AT wasilewskaeliza morbidityclinicalcourseandvaccinationagainstsarscov2virusinpatientswithduchennemusculardystrophyapatientreportedsurvey
AT sobierajskarekagnieszka morbidityclinicalcourseandvaccinationagainstsarscov2virusinpatientswithduchennemusculardystrophyapatientreportedsurvey
AT sledzinskakarolina morbidityclinicalcourseandvaccinationagainstsarscov2virusinpatientswithduchennemusculardystrophyapatientreportedsurvey
AT małgorzewiczsylwia morbidityclinicalcourseandvaccinationagainstsarscov2virusinpatientswithduchennemusculardystrophyapatientreportedsurvey
AT jassemewa morbidityclinicalcourseandvaccinationagainstsarscov2virusinpatientswithduchennemusculardystrophyapatientreportedsurvey
AT wierzbajolanta morbidityclinicalcourseandvaccinationagainstsarscov2virusinpatientswithduchennemusculardystrophyapatientreportedsurvey