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Expression of Proton-Sensitive GPR31, GPR151, TASK1 and TASK3 in Common Skin Tumors

TWIK-related acid-sensitive potassium channels TASK1 and TASK3, as well as the G-protein-coupled receptors GPR31 and GPR151, are proton-sensitive membrane proteins. They can be activated or inhibited by low extracellular pH (pHe), which is a hallmark of the tumor microenvironment in solid tumors. Ho...

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Detalles Bibliográficos
Autores principales: Förch, Antonia, Wallner, Susanne, Zeman, Florian, Ettl, Tobias, Brochhausen, Christoph, Schreml, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744809/
https://www.ncbi.nlm.nih.gov/pubmed/35011589
http://dx.doi.org/10.3390/cells11010027