The Dynamics of β-Amyloid Proteoforms Accumulation in the Brain of a 5xFAD Mouse Model of Alzheimer’s Disease

Alzheimer’s disease (AD) is the leading cause of dementia among the elderly. Neuropathologically, AD is characterized by the deposition of a 39- to 42-amino acid long β-amyloid (Aβ) peptide in the form of senile plaques. Several post-translational modifications (PTMs) in the N-terminal domain have b...

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Detalles Bibliográficos
Autores principales: Bugrova, Anna E., Strelnikova, Polina A., Indeykina, Maria I., Kononikhin, Alexey S., Zakharova, Natalia V., Brzhozovskiy, Alexander G., Barykin, Evgeny P., Pekov, Stanislav I., Gavrish, Maria S., Babaev, Alexey A., Kosyreva, Anna M., Morozova, Anna Y., Degterev, Daniil A., Mitkevich, Vladimir A., Popov, Igor A., Makarov, Alexander A., Nikolaev, Evgeny N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745018/
https://www.ncbi.nlm.nih.gov/pubmed/35008451
http://dx.doi.org/10.3390/ijms23010027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745018/
https://www.ncbi.nlm.nih.gov/pubmed/35008451
http://dx.doi.org/10.3390/ijms23010027

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