Cargando…

Mapping and Characterization of HCMV-Specific Unconventional HLA-E-Restricted CD8 T Cell Populations and Associated NK and T Cell Responses Using HLA/Peptide Tetramers and Spectral Flow Cytometry

HCMV drives complex and multiple cellular immune responses, which causes a persistent immune imprint in hosts. This study aimed to achieve both a quantitative determination of the frequency for various anti-HCMV immune cell subsets, including CD8 T, γδT, NK cells, and a qualitative analysis of their...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rousselière, Amélie, Delbos, Laurence, Bressollette, Céline, Berthaume, Maïlys, Charreau, Béatrice
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745070/ https://www.ncbi.nlm.nih.gov/pubmed/35008688 http://dx.doi.org/10.3390/ijms23010263

Ejemplares similares

Distinctive phenotype for HLA-E- versus HLA-A2-restricted memory CD8 αβT cells in the course of HCMV infection discloses features shared with NKG2C(+)CD57(+)NK and δ2(-)γδT cell subsets
por: Rousselière, Amélie, et al.
Publicado: (2022)

Persistent CD8 T Cell Marks Caused by the HCMV Infection in Seropositive Adults: Prevalence of HLA-E-Reactive CD8 T Cells
por: Rousselière, Amélie, et al.
Publicado: (2023)

HCMV triggers frequent and persistent UL40-specific unconventional HLA-E-restricted CD8 T-cell responses with potential autologous and allogeneic peptide recognition
por: Jouand, Nicolas, et al.
Publicado: (2018)

Changes in HCMV immune cell frequency and phenotype are associated with chronic lung allograft dysfunction
por: Rousselière, Amélie, et al.
Publicado: (2023)

Identification and HLA-Tetramer-Validation of Human CD4(+) and CD8(+) T Cell Responses against HCMV Proteins IE1 and IE2
por: Braendstrup, Peter, et al.
Publicado: (2014)

Identification of HIV-1-specific regulatory T cells using HLA-class-II tetramers
por: Angin, M, et al.
Publicado: (2012)

The HCMV membrane glycoprotein US10 selectively targets HLA-G for degradation
por: Park, Boyoun, et al.
Publicado: (2010)

Regulation of NK-Cell Function by HLA Class II
por: Niehrs, Annika, et al.
Publicado: (2020)

Detection of GAD65 Autoreactive T-Cells by HLA Class I Tetramers in Type 1 Diabetic Patients
por: Giuliani, Laura, et al.
Publicado: (2009)

Activation of NK Cells by an Endocytosed Receptor for Soluble HLA-G
por: Rajagopalan, Sumati, et al.
Publicado: (2006)

Tuning of human NK cells by endogenous HLA-C expression
por: Goodson-Gregg, Frederick J., et al.
Publicado: (2020)

HLA Class II tetramers reveal tissue-specific regulatory T cells that suppress T-cell responses in breast carcinoma patients
por: Schmidt, Hans-Henning, et al.
Publicado: (2013)

The UFM1 Pathway Impacts HCMV US2-Mediated Degradation of HLA Class I
por: Schuren, A.B.C., et al.
Publicado: (2021)

Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA–peptide tetramers
por: Cobbold, Mark, et al.
Publicado: (2005)

Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis
por: Gerstner, Christina, et al.
Publicado: (2020)

Biology and Clinical Relevance of HCMV-Associated Adaptive NK Cells
por: Gao, Fei, et al.
Publicado: (2022)

Identification of HLA-A*2402-restricted HCMV immediate early-1 (IE-1) epitopes as targets for CD8+ HCMV-specific cytotoxic T lymphocytes
por: Lim, Jong-Baeck, et al.
Publicado: (2009)

KIR-HLA footprints and NK cell-mediated recognition of HIV-1
por: Thobakgale, CF, et al.
Publicado: (2012)

Co-expression of HLA-E and HLA-G on genetically modified porcine endothelial cells attenuates human NK cell-mediated degranulation
por: Cross-Najafi, Arthur A., et al.
Publicado: (2023)

Use of HLA-B27 tetramers to identify low-frequency antigen-specific T cells in Chlamydia-triggered reactive arthritis
por: Appel, Heiner, et al.
Publicado: (2004)

Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining
por: Uchtenhagen, Hannes, et al.
Publicado: (2016)

The polymorphism at residue 156 determines the HLA-B*35 restricted peptide repertoire during HCMV infection
por: Abels, Wiebke C., et al.
Publicado: (2018)

Canonical and Cross-reactive Binding of NK Cell Inhibitory Receptors to HLA-C Allotypes Is Dictated by Peptides Bound to HLA-C
por: Sim, Malcolm J. W., et al.
Publicado: (2017)

Mycobacterium tuberculosis peptide E7/HLA-DRB1 tetramers with different HLA-DR alleles bound CD4(+) T cells might share identical CDR3 region
por: Gan, Yichuan, et al.
Publicado: (2018)

Impact of HCMV Infection on NK Cell Development and Function after HSCT
por: Della Chiesa, Mariella, et al.
Publicado: (2013)

Impact of cryopreservation on tetramer, cytokine flow cytometry, and ELISPOT
por: Maecker, Holden T, et al.
Publicado: (2005)

Generation of functional HLA-DR*1101 tetramers receptive for loading with pathogen or tumour derived synthetic peptides
por: Moro, Monica, et al.
Publicado: (2005)

HLA-E Peptide Repertoire and Dimorphism—Centerpieces in the Adaptive NK Cell Puzzle?
por: Rölle, Alexander, et al.
Publicado: (2018)

NK Cell Alloreactivity against KIR-Ligand-Mismatched HLA-Haploidentical Tissue Derived from HLA Haplotype-Homozygous iPSCs
por: Ichise, Hiroshi, et al.
Publicado: (2017)

Allopurinol non-covalently facilitates binding of unconventional peptides to HLA-B*58:01
por: Huan, Xuelu, et al.
Publicado: (2023)

HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells
por: Gornalusse, Germán G., et al.
Publicado: (2017)

HLA-E-Restricted Cross-Recognition of Allogeneic Endothelial Cells by CMV-Associated CD8 T Cells: A Potential Risk Factor following Transplantation
por: Allard, Mathilde, et al.
Publicado: (2012)

NK Cells from RAG- or DCLRE1C-Deficient Patients Inhibit HCMV
por: Wu, Zeguang, et al.
Publicado: (2019)

NK Cells Equipped With a Chimeric Antigen Receptor That Overcomes Inhibition by HLA Class I for Adoptive Transfer of CAR-NK Cells
por: Zhuang, Xiaoxuan, et al.
Publicado: (2022)

Susceptibility of Human Melanoma Cells to Autologous Natural Killer (NK) Cell Killing: HLA-Related Effector Mechanisms and Role of Unlicensed NK Cells
por: Carrega, Paolo, et al.
Publicado: (2009)

Identification of an elaborate NK-specific system regulating HLA-C expression
por: Li, Hongchuan, et al.
Publicado: (2018)

Selinexor Enhances NK Cell Activation Against Malignant B Cells via Downregulation of HLA-E
por: Fisher, Jack G., et al.
Publicado: (2021)

Host KIR/HLA-C Genotypes Determine HIV-Mediated Changes of the NK Cell Repertoire and Are Associated With Vpu Sequence Variations Impacting Downmodulation of HLA-C
por: Vollmers, Sarah, et al.
Publicado: (2022)

HLA-B and HLA-C Differ in Their Nanoscale Organization at Cell Surfaces
por: Kennedy, Philippa R., et al.
Publicado: (2019)

Association of HLA-A and Non-Classical HLA Class I Alleles
por: Carlini, Federico, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_e761hok38alnhfq8jonkjtki73