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Inducing Energetic Switching Using Klotho Improves Vascular Smooth Muscle Cell Phenotype

The cardiovascular disease of atherosclerosis is characterised by aged vascular smooth muscle cells and compromised cell survival. Analysis of human and murine plaques highlights markers of DNA damage such as p53, Ataxia telangiectasia mutated (ATM), and defects in mitochondrial oxidative metabolism...

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Detalles Bibliográficos
Autores principales: Docherty, Craig K., Strembitska, Anastasiya, Baker, Christa P., Schmidt, Fiona F., Reay, Kieran, Mercer, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745077/
https://www.ncbi.nlm.nih.gov/pubmed/35008643
http://dx.doi.org/10.3390/ijms23010217