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Inducing Energetic Switching Using Klotho Improves Vascular Smooth Muscle Cell Phenotype
The cardiovascular disease of atherosclerosis is characterised by aged vascular smooth muscle cells and compromised cell survival. Analysis of human and murine plaques highlights markers of DNA damage such as p53, Ataxia telangiectasia mutated (ATM), and defects in mitochondrial oxidative metabolism...
Autores principales: | Docherty, Craig K., Strembitska, Anastasiya, Baker, Christa P., Schmidt, Fiona F., Reay, Kieran, Mercer, John R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745077/ https://www.ncbi.nlm.nih.gov/pubmed/35008643 http://dx.doi.org/10.3390/ijms23010217 |
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