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EDEM1 Regulates Amyloid Precursor Protein (APP) Metabolism and Amyloid-β Production
Endoplasmic reticulum (ER) degradation-enhancing α-mannosidase-like protein 1 (EDEM1) is a quality control factor directly involved in the endoplasmic reticulum-associated degradation (ERAD) process. It recognizes terminally misfolded proteins and directs them to retrotranslocation which is followed...
Autores principales: | Nowakowska-Gołacka, Jowita, Czapiewska, Justyna, Sominka, Hanna, Sowa-Rogozińska, Natalia, Słomińska-Wojewódzka, Monika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745108/ https://www.ncbi.nlm.nih.gov/pubmed/35008544 http://dx.doi.org/10.3390/ijms23010117 |
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