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CD147 Is Essential for the Development of Psoriasis via the Induction of Th17 Cell Differentiation
Th17 cells play an important role in psoriasis. The differentiation of naïve CD4(+) T cells into Th17 cells depends on glycolysis as the energy source. CD147/basigin, an integral transmembrane protein belonging to the immunoglobulin superfamily, regulates glycolysis in association with monocarboxyla...
Autores principales: | Okubo, Aoi, Uchida, Youhei, Higashi, Yuko, Sato, Takuya, Ogawa, Youichi, Ryuge, Akihiro, Kadomatsu, Kenji, Kanekura, Takuro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745261/ https://www.ncbi.nlm.nih.gov/pubmed/35008603 http://dx.doi.org/10.3390/ijms23010177 |
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