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Integrative Study of the Structural and Dynamical Properties of a KirBac3.1 Mutant: Functional Implication of a Highly Conserved Tryptophan in the Transmembrane Domain

ATP-sensitive potassium (K-ATP) channels are ubiquitously expressed on the plasma membrane of cells in several organs, including the heart, pancreas, and brain, and they govern a wide range of physiological processes. In pancreatic β-cells, K-ATP channels composed of Kir6.2 and SUR1 play a key role...

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Detalles Bibliográficos
Autores principales:	Fagnen, Charline, Bannwarth, Ludovic, Oubella, Iman, Zuniga, Dania, Haouz, Ahmed, Forest, Eric, Scala, Rosa, Bendahhou, Saïd, De Zorzi, Rita, Perahia, David, Vénien-Bryan, Catherine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745282/ https://www.ncbi.nlm.nih.gov/pubmed/35008764 http://dx.doi.org/10.3390/ijms23010335

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