Generation of Lasso Peptide-Based ClpP Binders

The Clp protease system fulfills a plethora of important functions in bacteria. It consists of a tetradecameric ClpP barrel holding the proteolytic centers and two hexameric Clp-ATPase rings, which recognize, unfold, and then feed substrate proteins into the ClpP barrel for proteolytic degradation....

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Detalles Bibliográficos
Autores principales: Malik, Imran T., Hegemann, Julian D., Brötz-Oesterhelt, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745299/
https://www.ncbi.nlm.nih.gov/pubmed/35008890
http://dx.doi.org/10.3390/ijms23010465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745299/
https://www.ncbi.nlm.nih.gov/pubmed/35008890
http://dx.doi.org/10.3390/ijms23010465

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