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Generation of Lasso Peptide-Based ClpP Binders
The Clp protease system fulfills a plethora of important functions in bacteria. It consists of a tetradecameric ClpP barrel holding the proteolytic centers and two hexameric Clp-ATPase rings, which recognize, unfold, and then feed substrate proteins into the ClpP barrel for proteolytic degradation....
Autores principales: | Malik, Imran T., Hegemann, Julian D., Brötz-Oesterhelt, Heike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745299/ https://www.ncbi.nlm.nih.gov/pubmed/35008890 http://dx.doi.org/10.3390/ijms23010465 |
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