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Heat Shock Protein 60 Restricts Release of Mitochondrial dsRNA to Suppress Hepatic Inflammation and Ameliorate Non-Alcoholic Fatty Liver Disease in Mice

Non-alcoholic fatty liver disease (NAFLD), the most common cause of chronic liver disease, consists of fat deposited (steatosis) in the liver due to causes besides excessive alcohol use. The folding activity of heat shock protein 60 (HSP60) has been shown to protect mitochondria from proteotoxicity...

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Detalles Bibliográficos
Autores principales: Huang, Ying-Hsien, Wang, Feng-Sheng, Wang, Pei-Wen, Lin, Hung-Yu, Luo, Sheng-Dean, Yang, Ya-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745303/
https://www.ncbi.nlm.nih.gov/pubmed/35009003
http://dx.doi.org/10.3390/ijms23010577