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Increased Risk of Aortic Dissection with Perlecan Deficiency

Perlecan (HSPG2), a basement membrane-type heparan sulfate proteoglycan, has been implicated in the development of aortic tissue. However, its role in the development and maintenance of the aortic wall remains unknown. Perlecan-deficient mice (Hspg2(−/−)-Tg: Perl KO) have been found to show a high f...

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Detalles Bibliográficos
Autores principales:	Nonaka, Risa, Iesaki, Takafumi, Kerever, Aurelien, Arikawa-Hirasawa, Eri
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745340/ https://www.ncbi.nlm.nih.gov/pubmed/35008739 http://dx.doi.org/10.3390/ijms23010315

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