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Green Efficient One-Pot Synthesis and Separation of Nitrones in Water Assisted by a Self-Assembled Nanoreactor

This article reports an alternative method for preparing nitrones using a tetrahedral capsule as a nanoreactor in water. Using the hydrophobic cavity of the capsule allowed us to reduce the reaction times and easily separate the nitrones from the reaction mixture, obtaining reaction yields equal or...

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Detalles Bibliográficos
Autores principales: Patamia, Vincenzo, Floresta, Giuseppe, Pistarà, Venerando, Rescifina, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745384/
https://www.ncbi.nlm.nih.gov/pubmed/35008661
http://dx.doi.org/10.3390/ijms23010236
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author Patamia, Vincenzo
Floresta, Giuseppe
Pistarà, Venerando
Rescifina, Antonio
author_facet Patamia, Vincenzo
Floresta, Giuseppe
Pistarà, Venerando
Rescifina, Antonio
author_sort Patamia, Vincenzo
collection PubMed
description This article reports an alternative method for preparing nitrones using a tetrahedral capsule as a nanoreactor in water. Using the hydrophobic cavity of the capsule allowed us to reduce the reaction times and easily separate the nitrones from the reaction mixture, obtaining reaction yields equal or comparable to those obtained with the methods already reported. Furthermore, at the basis of this methodology, there is an eco-friendly approach carried out that can certainly be extended to other synthesis methods for the preparation of other substrates by exploiting various types of macrocyclic hosts, suitably designed and widely used in supramolecular chemistry.
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spelling pubmed-87453842022-01-11 Green Efficient One-Pot Synthesis and Separation of Nitrones in Water Assisted by a Self-Assembled Nanoreactor Patamia, Vincenzo Floresta, Giuseppe Pistarà, Venerando Rescifina, Antonio Int J Mol Sci Communication This article reports an alternative method for preparing nitrones using a tetrahedral capsule as a nanoreactor in water. Using the hydrophobic cavity of the capsule allowed us to reduce the reaction times and easily separate the nitrones from the reaction mixture, obtaining reaction yields equal or comparable to those obtained with the methods already reported. Furthermore, at the basis of this methodology, there is an eco-friendly approach carried out that can certainly be extended to other synthesis methods for the preparation of other substrates by exploiting various types of macrocyclic hosts, suitably designed and widely used in supramolecular chemistry. MDPI 2021-12-26 /pmc/articles/PMC8745384/ /pubmed/35008661 http://dx.doi.org/10.3390/ijms23010236 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Patamia, Vincenzo
Floresta, Giuseppe
Pistarà, Venerando
Rescifina, Antonio
Green Efficient One-Pot Synthesis and Separation of Nitrones in Water Assisted by a Self-Assembled Nanoreactor
title Green Efficient One-Pot Synthesis and Separation of Nitrones in Water Assisted by a Self-Assembled Nanoreactor
title_full Green Efficient One-Pot Synthesis and Separation of Nitrones in Water Assisted by a Self-Assembled Nanoreactor
title_fullStr Green Efficient One-Pot Synthesis and Separation of Nitrones in Water Assisted by a Self-Assembled Nanoreactor
title_full_unstemmed Green Efficient One-Pot Synthesis and Separation of Nitrones in Water Assisted by a Self-Assembled Nanoreactor
title_short Green Efficient One-Pot Synthesis and Separation of Nitrones in Water Assisted by a Self-Assembled Nanoreactor
title_sort green efficient one-pot synthesis and separation of nitrones in water assisted by a self-assembled nanoreactor
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745384/
https://www.ncbi.nlm.nih.gov/pubmed/35008661
http://dx.doi.org/10.3390/ijms23010236
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