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Green Efficient One-Pot Synthesis and Separation of Nitrones in Water Assisted by a Self-Assembled Nanoreactor
This article reports an alternative method for preparing nitrones using a tetrahedral capsule as a nanoreactor in water. Using the hydrophobic cavity of the capsule allowed us to reduce the reaction times and easily separate the nitrones from the reaction mixture, obtaining reaction yields equal or...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745384/ https://www.ncbi.nlm.nih.gov/pubmed/35008661 http://dx.doi.org/10.3390/ijms23010236 |
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author | Patamia, Vincenzo Floresta, Giuseppe Pistarà, Venerando Rescifina, Antonio |
author_facet | Patamia, Vincenzo Floresta, Giuseppe Pistarà, Venerando Rescifina, Antonio |
author_sort | Patamia, Vincenzo |
collection | PubMed |
description | This article reports an alternative method for preparing nitrones using a tetrahedral capsule as a nanoreactor in water. Using the hydrophobic cavity of the capsule allowed us to reduce the reaction times and easily separate the nitrones from the reaction mixture, obtaining reaction yields equal or comparable to those obtained with the methods already reported. Furthermore, at the basis of this methodology, there is an eco-friendly approach carried out that can certainly be extended to other synthesis methods for the preparation of other substrates by exploiting various types of macrocyclic hosts, suitably designed and widely used in supramolecular chemistry. |
format | Online Article Text |
id | pubmed-8745384 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87453842022-01-11 Green Efficient One-Pot Synthesis and Separation of Nitrones in Water Assisted by a Self-Assembled Nanoreactor Patamia, Vincenzo Floresta, Giuseppe Pistarà, Venerando Rescifina, Antonio Int J Mol Sci Communication This article reports an alternative method for preparing nitrones using a tetrahedral capsule as a nanoreactor in water. Using the hydrophobic cavity of the capsule allowed us to reduce the reaction times and easily separate the nitrones from the reaction mixture, obtaining reaction yields equal or comparable to those obtained with the methods already reported. Furthermore, at the basis of this methodology, there is an eco-friendly approach carried out that can certainly be extended to other synthesis methods for the preparation of other substrates by exploiting various types of macrocyclic hosts, suitably designed and widely used in supramolecular chemistry. MDPI 2021-12-26 /pmc/articles/PMC8745384/ /pubmed/35008661 http://dx.doi.org/10.3390/ijms23010236 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Communication Patamia, Vincenzo Floresta, Giuseppe Pistarà, Venerando Rescifina, Antonio Green Efficient One-Pot Synthesis and Separation of Nitrones in Water Assisted by a Self-Assembled Nanoreactor |
title | Green Efficient One-Pot Synthesis and Separation of Nitrones in Water Assisted by a Self-Assembled Nanoreactor |
title_full | Green Efficient One-Pot Synthesis and Separation of Nitrones in Water Assisted by a Self-Assembled Nanoreactor |
title_fullStr | Green Efficient One-Pot Synthesis and Separation of Nitrones in Water Assisted by a Self-Assembled Nanoreactor |
title_full_unstemmed | Green Efficient One-Pot Synthesis and Separation of Nitrones in Water Assisted by a Self-Assembled Nanoreactor |
title_short | Green Efficient One-Pot Synthesis and Separation of Nitrones in Water Assisted by a Self-Assembled Nanoreactor |
title_sort | green efficient one-pot synthesis and separation of nitrones in water assisted by a self-assembled nanoreactor |
topic | Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745384/ https://www.ncbi.nlm.nih.gov/pubmed/35008661 http://dx.doi.org/10.3390/ijms23010236 |
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