Blood Pressure Elevation of Tubular Specific (P)RR Transgenic Mice and Lethal Tubular Degeneration due to Possible Intracellular Interactions between (P)RR and Alternative Renin Products

The prorenin/renin receptor ((P)RR) is a multifunctional protein that is widely distributed in various organs. Despite intensive research for more than 20 years, this receptor has not been fully characterized. In this study, we generated mice overexpressing the tubular epithelial (P)RR gene ((P)RR-T...

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Detalles Bibliográficos
Autores principales: Saigo, Sae, Kino, Tabito, Uchida, Kotaro, Sugawara, Takuya, Chen, Lin, Sugiyama, Michiko, Azushima, Kengo, Wakui, Hiromichi, Tamura, Kouichi, Ishigami, Tomoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745386/
https://www.ncbi.nlm.nih.gov/pubmed/35008728
http://dx.doi.org/10.3390/ijms23010302

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