Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway

Osteosarcoma is a highly common malignant bone tumor. Its highly metastatic properties are the leading cause of mortality for cancer. Niclosamide, a salicylanilide derivative, is an oral antihelminthic drug of known anticancer potential. However, the effect of niclosamide on osteosarcoma cell migrat...

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Detalles Bibliográficos
Autores principales: Yeh, Liang-Tsai, Lin, Chiao-Wen, Lu, Ko-Hsiu, Hsieh, Yi-Hsien, Yeh, Chao-Bin, Yang, Shun-Fa, Yang, Jia-Sin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745393/
https://www.ncbi.nlm.nih.gov/pubmed/35008910
http://dx.doi.org/10.3390/ijms23010484