Cargando…
Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway
Osteosarcoma is a highly common malignant bone tumor. Its highly metastatic properties are the leading cause of mortality for cancer. Niclosamide, a salicylanilide derivative, is an oral antihelminthic drug of known anticancer potential. However, the effect of niclosamide on osteosarcoma cell migrat...
Autores principales: | Yeh, Liang-Tsai, Lin, Chiao-Wen, Lu, Ko-Hsiu, Hsieh, Yi-Hsien, Yeh, Chao-Bin, Yang, Shun-Fa, Yang, Jia-Sin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745393/ https://www.ncbi.nlm.nih.gov/pubmed/35008910 http://dx.doi.org/10.3390/ijms23010484 |
Ejemplares similares
-
Tomatidine Represses Invasion and Migration of Human Osteosarcoma U2OS and HOS Cells by Suppression of Presenilin 1 and c-Raf–MEK–ERK Pathway
por: Hsieh, Min-Hong, et al.
Publicado: (2020) -
Lipocalin-2 Inhibits Osteosarcoma Cell Metastasis by Suppressing MET Expression via the MEK–ERK Pathway
por: Lu, Ko-Hsiu, et al.
Publicado: (2021) -
Nobiletin inhibits human osteosarcoma cells metastasis by blocking ERK and JNK-mediated MMPs expression
por: Cheng, Hsin-Lin, et al.
Publicado: (2016) -
Zoledronate blocks geranylgeranylation not farnesylation to suppress human osteosarcoma U2OS cells metastasis by EMT via Rho A activation and FAK-inhibited JNK and p38 pathways
por: Cheng, Hsin-Lin, et al.
Publicado: (2016) -
HO-3867 Induces Apoptosis via the JNK Signaling Pathway in Human Osteosarcoma Cells
por: Lu, Peace Wun-Ang, et al.
Publicado: (2022)