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Pharmacologically induced endolysosomal cholesterol imbalance through clinically licensed drugs itraconazole and fluoxetine impairs Ebola virus infection in vitro

Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus (EBOV). The latest occasional EVD outbreak (2013–2016) in Western African, which was accompanied by a high fatality rate, showed the great potential of epidemic and pandemic spread. Antiviral therapies against...

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Detalles Bibliográficos
Autores principales: Kummer, Susann, Lander, Angelika, Goretzko, Jonas, Kirchoff, Norman, Rescher, Ursula, Schloer, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745396/
https://www.ncbi.nlm.nih.gov/pubmed/34919035
http://dx.doi.org/10.1080/22221751.2021.2020598

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