Thymosin β4 Is an Endogenous Iron Chelator and Molecular Switcher of Ferroptosis

Thymosin β4 (Tβ4) was extracted forty years agofrom calf thymus. Since then, it has been identified as a G-actin binding protein involved in blood clotting, tissue regeneration, angiogenesis, and anti-inflammatory processes. Tβ4 has also been implicated in tumor metastasis and neurodegeneration. How...

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Detalles Bibliográficos
Autores principales: Lachowicz, Joanna I., Pichiri, Giusi, Piludu, Marco, Fais, Sara, Orrù, Germano, Congiu, Terenzio, Piras, Monica, Faa, Gavino, Fanni, Daniela, Dalla Torre, Gabriele, Lopez, Xabier, Chandra, Kousik, Szczepski, Kacper, Jaremko, Lukasz, Ghosh, Mitra, Emwas, Abdul-Hamid, Castagnola, Massimo, Jaremko, Mariusz, Hannappel, Ewald, Coni, Pierpaolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745404/
https://www.ncbi.nlm.nih.gov/pubmed/35008976
http://dx.doi.org/10.3390/ijms23010551

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