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Weakening or Structural Strengthening? An Evaluation of Bone Density after MRgFUS Ablation for Treatment of Benign Bone Lesions

Previous studies suggest that interventional ablative procedures on bone lesions may weaken the bone, especially when performed through the needle approach. Our purpose was to evaluate, through Computed Tomography (CT), the effects of Magnetic Resonance guided Focused Ultrasound Surgery (MRgFUS) abl...

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Autores principales: de Cataldo, Camilla, Bruno, Federico, Necozione, Stefano, Novello, Mariangela, Palumbo, Pierpaolo, Zugaro, Luigi, Barile, Antonio, Masciocchi, Carlo, Arrigoni, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745457/
https://www.ncbi.nlm.nih.gov/pubmed/35011923
http://dx.doi.org/10.3390/jcm11010182
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author de Cataldo, Camilla
Bruno, Federico
Necozione, Stefano
Novello, Mariangela
Palumbo, Pierpaolo
Zugaro, Luigi
Barile, Antonio
Masciocchi, Carlo
Arrigoni, Francesco
author_facet de Cataldo, Camilla
Bruno, Federico
Necozione, Stefano
Novello, Mariangela
Palumbo, Pierpaolo
Zugaro, Luigi
Barile, Antonio
Masciocchi, Carlo
Arrigoni, Francesco
author_sort de Cataldo, Camilla
collection PubMed
description Previous studies suggest that interventional ablative procedures on bone lesions may weaken the bone, especially when performed through the needle approach. Our purpose was to evaluate, through Computed Tomography (CT), the effects of Magnetic Resonance guided Focused Ultrasound Surgery (MRgFUS) ablation on painful osteoid osteomas and osteoblastomas in terms of bone density and morphological changes. We retrospectively evaluated patients treated at our institution with MRgFUS for superficial, painful osteoid osteoma or osteoblastoma during the last 9 years. Inclusion criteria were procedural and clinical success, as well as the availability of pre- and postprocedural CT examinations. Imaging features assessed were perilesional/nidus density changes and the occurrence of pathological fractures during the follow-up period. Our study population included 31 osteoid osteomas and 5 intra-articular osteoblastomas in 36 treated patients. We found an increased bone density of the lesions when pre and post-treatment CT- values were compared: these differences were statistically significant, and this finding is consistent with significant bone densification at the post-treatment imaging follow-up. No pathological fractures were observed after ablation during the follow-up. MRgFUS can be considered to be the treatment of choice for benign superficial bone lesions, thanks to its minimal invasiveness, excellent effectiveness, and safety. Pathological fractures, reported in literature as a rare event using needle ablation, never occurred in our MRgFUS treatment series.
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spelling pubmed-87454572022-01-11 Weakening or Structural Strengthening? An Evaluation of Bone Density after MRgFUS Ablation for Treatment of Benign Bone Lesions de Cataldo, Camilla Bruno, Federico Necozione, Stefano Novello, Mariangela Palumbo, Pierpaolo Zugaro, Luigi Barile, Antonio Masciocchi, Carlo Arrigoni, Francesco J Clin Med Article Previous studies suggest that interventional ablative procedures on bone lesions may weaken the bone, especially when performed through the needle approach. Our purpose was to evaluate, through Computed Tomography (CT), the effects of Magnetic Resonance guided Focused Ultrasound Surgery (MRgFUS) ablation on painful osteoid osteomas and osteoblastomas in terms of bone density and morphological changes. We retrospectively evaluated patients treated at our institution with MRgFUS for superficial, painful osteoid osteoma or osteoblastoma during the last 9 years. Inclusion criteria were procedural and clinical success, as well as the availability of pre- and postprocedural CT examinations. Imaging features assessed were perilesional/nidus density changes and the occurrence of pathological fractures during the follow-up period. Our study population included 31 osteoid osteomas and 5 intra-articular osteoblastomas in 36 treated patients. We found an increased bone density of the lesions when pre and post-treatment CT- values were compared: these differences were statistically significant, and this finding is consistent with significant bone densification at the post-treatment imaging follow-up. No pathological fractures were observed after ablation during the follow-up. MRgFUS can be considered to be the treatment of choice for benign superficial bone lesions, thanks to its minimal invasiveness, excellent effectiveness, and safety. Pathological fractures, reported in literature as a rare event using needle ablation, never occurred in our MRgFUS treatment series. MDPI 2021-12-29 /pmc/articles/PMC8745457/ /pubmed/35011923 http://dx.doi.org/10.3390/jcm11010182 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
de Cataldo, Camilla
Bruno, Federico
Necozione, Stefano
Novello, Mariangela
Palumbo, Pierpaolo
Zugaro, Luigi
Barile, Antonio
Masciocchi, Carlo
Arrigoni, Francesco
Weakening or Structural Strengthening? An Evaluation of Bone Density after MRgFUS Ablation for Treatment of Benign Bone Lesions
title Weakening or Structural Strengthening? An Evaluation of Bone Density after MRgFUS Ablation for Treatment of Benign Bone Lesions
title_full Weakening or Structural Strengthening? An Evaluation of Bone Density after MRgFUS Ablation for Treatment of Benign Bone Lesions
title_fullStr Weakening or Structural Strengthening? An Evaluation of Bone Density after MRgFUS Ablation for Treatment of Benign Bone Lesions
title_full_unstemmed Weakening or Structural Strengthening? An Evaluation of Bone Density after MRgFUS Ablation for Treatment of Benign Bone Lesions
title_short Weakening or Structural Strengthening? An Evaluation of Bone Density after MRgFUS Ablation for Treatment of Benign Bone Lesions
title_sort weakening or structural strengthening? an evaluation of bone density after mrgfus ablation for treatment of benign bone lesions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745457/
https://www.ncbi.nlm.nih.gov/pubmed/35011923
http://dx.doi.org/10.3390/jcm11010182
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