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Relevance of AIF/CypA Lethal Pathway in SH-SY5Y Cells Treated with Staurosporine

The AIF/CypA complex exerts a lethal activity in several rodent models of acute brain injury. Upon formation, it translocates into the nucleus of cells receiving apoptotic stimuli, inducing chromatin condensation, DNA fragmentation, and cell death by a caspase-independent mechanism. Inhibition of th...

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Detalles Bibliográficos
Autores principales:	Conte, Mariarosaria, Palumbo, Rosanna, Monti, Alessandra, Fontana, Elisabetta, Nebbioso, Angela, Ruvo, Menotti, Altucci, Lucia, Doti, Nunzianna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745523/ https://www.ncbi.nlm.nih.gov/pubmed/35008690 http://dx.doi.org/10.3390/ijms23010265

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