Evaluating a Targeted Cancer Therapy Approach Mediated by RNA trans-Splicing In Vitro and in a Xenograft Model for Epidermolysis Bullosa-Associated Skin Cancer

Conventional anti-cancer therapies based on chemo- and/or radiotherapy represent highly effective means to kill cancer cells but lack tumor specificity and, therefore, result in a wide range of iatrogenic effects. A promising approach to overcome this obstacle is spliceosome-mediated RNA trans-splic...

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Detalles Bibliográficos
Autores principales: Woess, Katharina, Sun, Yuchen, Morio, Hanae, Stierschneider, Anna, Kaufmann, Anna, Hainzl, Stefan, Trattner, Lisa, Kocher, Thomas, Tockner, Birgit, Leb-Reichl, Victoria, Steiner, Markus, Brachtl, Gabriele, South, Andrew P., Bauer, Johann W., Reichelt, Julia, Furihata, Tomomi, Wally, Verena, Koller, Ulrich, Piñón Hofbauer, Josefina, Guttmann-Gruber, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745581/
https://www.ncbi.nlm.nih.gov/pubmed/35008999
http://dx.doi.org/10.3390/ijms23010575

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