Therapeutic Effects of Hypoxic and Pro-Inflammatory Priming of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Inflammatory Arthritis

Mesenchymal stem cells (MSCs) immunomodulate inflammatory responses through paracrine signalling, including via secretion of extracellular vesicles (EVs) in the cell secretome. We evaluated the therapeutic potential of MSCs-derived small EVs in an antigen-induced model of arthritis (AIA). EVs isolat...

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Detalles Bibliográficos
Autores principales: Kay, Alasdair G., Treadwell, Kane, Roach, Paul, Morgan, Rebecca, Lodge, Rhys, Hyland, Mairead, Piccinini, Anna M., Forsyth, Nicholas R., Kehoe, Oksana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745583/
https://www.ncbi.nlm.nih.gov/pubmed/35008555
http://dx.doi.org/10.3390/ijms23010126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745583/
https://www.ncbi.nlm.nih.gov/pubmed/35008555
http://dx.doi.org/10.3390/ijms23010126

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