Homologous Recombination Deficiencies and Hereditary Tumors

Homologous recombination (HR) is a vital process for repairing DNA double-strand breaks. Germline variants in the HR pathway, comprising at least 10 genes, such as BRCA1, BRCA2, ATM, BARD1, BRIP1, CHEK2, NBS1(NBN), PALB2, RAD51C, and RAD51D, lead to inherited susceptibility to specific types of canc...

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Detalles Bibliográficos
Autores principales: Yamamoto, Hideki, Hirasawa, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745585/
https://www.ncbi.nlm.nih.gov/pubmed/35008774
http://dx.doi.org/10.3390/ijms23010348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745585/
https://www.ncbi.nlm.nih.gov/pubmed/35008774
http://dx.doi.org/10.3390/ijms23010348

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