Resolvin D2 and Resolvin D1 Differentially Activate Protein Kinases to Counter-Regulate Histamine-Induced [Ca(2+)](i) Increase and Mucin Secretion in Conjunctival Goblet Cells

Resolvin (Rv) D2 and RvD1 are biosynthesized from docosahexaenoic acid (DHA) and promote resolution of inflammation in multiple organs and tissues, including the conjunctiva. Histamine is a mediator produced by mast cells in the conjunctiva during the allergic response. We determined the interaction...

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Detalles Bibliográficos
Autores principales: Yang, Menglu, Botten, Nora, Hodges, Robin, Bair, Jeffrey, Utheim, Tor P., Serhan, Charles N., Dartt, Darlene A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745650/
https://www.ncbi.nlm.nih.gov/pubmed/35008563
http://dx.doi.org/10.3390/ijms23010141

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