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Sleep Problems in Chronic Inflammatory Diseases: Prevalence, Treatment, and New Perspectives: A Narrative Review

Epidemiological studies have shown that individuals with sleep problems are at a greater risk of developing immune and chronic inflammatory diseases. As sleep disorders and low sleep quality in the general population are frequent ailments, it seems important to recognize them as serious public healt...

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Autores principales: Ditmer, Marta, Gabryelska, Agata, Turkiewicz, Szymon, Białasiewicz, Piotr, Małecka-Wojciesko, Ewa, Sochal, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745687/
https://www.ncbi.nlm.nih.gov/pubmed/35011807
http://dx.doi.org/10.3390/jcm11010067
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author Ditmer, Marta
Gabryelska, Agata
Turkiewicz, Szymon
Białasiewicz, Piotr
Małecka-Wojciesko, Ewa
Sochal, Marcin
author_facet Ditmer, Marta
Gabryelska, Agata
Turkiewicz, Szymon
Białasiewicz, Piotr
Małecka-Wojciesko, Ewa
Sochal, Marcin
author_sort Ditmer, Marta
collection PubMed
description Epidemiological studies have shown that individuals with sleep problems are at a greater risk of developing immune and chronic inflammatory diseases. As sleep disorders and low sleep quality in the general population are frequent ailments, it seems important to recognize them as serious public health problems. The exact relation between immunity and sleep remains elusive; however, it might be suspected that it is shaped by others stress and alterations of the circadian rhythm (commonly caused by for example shift work). As studies show, drugs used in the therapy of chronic inflammatory diseases, such as steroids or monoclonal antibodies, also influence sleep in more complex ways than those resulting from attenuation of the disease symptoms. Interestingly, the relation between sleep and immunity appears to be bidirectional; that is, sleep may influence the course of immune diseases, such as inflammatory bowel disease. Thus, proper diagnosis and treatment of sleep disorders are vital to the patient’s immune status and, in effect, health. This review examines the epidemiology of sleep disorders and immune diseases, the associations between them, and their current treatment and novel perspectives in therapy.
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spelling pubmed-87456872022-01-11 Sleep Problems in Chronic Inflammatory Diseases: Prevalence, Treatment, and New Perspectives: A Narrative Review Ditmer, Marta Gabryelska, Agata Turkiewicz, Szymon Białasiewicz, Piotr Małecka-Wojciesko, Ewa Sochal, Marcin J Clin Med Review Epidemiological studies have shown that individuals with sleep problems are at a greater risk of developing immune and chronic inflammatory diseases. As sleep disorders and low sleep quality in the general population are frequent ailments, it seems important to recognize them as serious public health problems. The exact relation between immunity and sleep remains elusive; however, it might be suspected that it is shaped by others stress and alterations of the circadian rhythm (commonly caused by for example shift work). As studies show, drugs used in the therapy of chronic inflammatory diseases, such as steroids or monoclonal antibodies, also influence sleep in more complex ways than those resulting from attenuation of the disease symptoms. Interestingly, the relation between sleep and immunity appears to be bidirectional; that is, sleep may influence the course of immune diseases, such as inflammatory bowel disease. Thus, proper diagnosis and treatment of sleep disorders are vital to the patient’s immune status and, in effect, health. This review examines the epidemiology of sleep disorders and immune diseases, the associations between them, and their current treatment and novel perspectives in therapy. MDPI 2021-12-23 /pmc/articles/PMC8745687/ /pubmed/35011807 http://dx.doi.org/10.3390/jcm11010067 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ditmer, Marta
Gabryelska, Agata
Turkiewicz, Szymon
Białasiewicz, Piotr
Małecka-Wojciesko, Ewa
Sochal, Marcin
Sleep Problems in Chronic Inflammatory Diseases: Prevalence, Treatment, and New Perspectives: A Narrative Review
title Sleep Problems in Chronic Inflammatory Diseases: Prevalence, Treatment, and New Perspectives: A Narrative Review
title_full Sleep Problems in Chronic Inflammatory Diseases: Prevalence, Treatment, and New Perspectives: A Narrative Review
title_fullStr Sleep Problems in Chronic Inflammatory Diseases: Prevalence, Treatment, and New Perspectives: A Narrative Review
title_full_unstemmed Sleep Problems in Chronic Inflammatory Diseases: Prevalence, Treatment, and New Perspectives: A Narrative Review
title_short Sleep Problems in Chronic Inflammatory Diseases: Prevalence, Treatment, and New Perspectives: A Narrative Review
title_sort sleep problems in chronic inflammatory diseases: prevalence, treatment, and new perspectives: a narrative review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745687/
https://www.ncbi.nlm.nih.gov/pubmed/35011807
http://dx.doi.org/10.3390/jcm11010067
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