Biomarkers of Castrate Resistance in Prostate Cancer: Androgen Receptor Amplification and T877A Mutation Detection by Multiplex Droplet Digital PCR

Androgen Receptor (AR) alterations (amplification, point mutations, and splice variants) are master players in metastatic castration resistant prostate cancer (CRPC) progression and central therapeutic targets for patient management. Here, we have developed two multiplexed droplet digital PCR (ddPCR...

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Detalles Bibliográficos
Autores principales: Young, Francis P., Becker, Therese M., Nimir, Mohammed, Opperman, Thomas, Chua, Wei, Balakrishnar, Bavanthi, de Souza, Paul, Ma, Yafeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745706/
https://www.ncbi.nlm.nih.gov/pubmed/35011998
http://dx.doi.org/10.3390/jcm11010257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745706/
https://www.ncbi.nlm.nih.gov/pubmed/35011998
http://dx.doi.org/10.3390/jcm11010257

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