MTEP, a Selective mGluR5 Antagonist, Had a Neuroprotective Effect but Did Not Prevent the Development of Spontaneous Recurrent Seizures and Behavioral Comorbidities in the Rat Lithium–Pilocarpine Model of Epilepsy

Metabotropic glutamate receptors (mGluRs) are expressed predominantly on neurons and glial cells and are involved in the modulation of a wide range of signal transduction cascades. Therefore, different subtypes of mGluRs are considered a promising target for the treatment of various brain diseases....

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Detalles Bibliográficos
Autores principales: Dyomina, Alexandra V., Kovalenko, Anna A., Zakharova, Maria V., Postnikova, Tatiana Yu., Griflyuk, Alexandra V., Smolensky, Ilya V., Antonova, Irina V., Zaitsev, Aleksey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745728/
https://www.ncbi.nlm.nih.gov/pubmed/35008924
http://dx.doi.org/10.3390/ijms23010497

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