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Association between CHADS(2), CHA(2)DS(2)-VASc, ATRIA, and Essen Stroke Risk Scores and Unsuccessful Recanalization after Endovascular Thrombectomy in Acute Ischemic Stroke Patients

Background: The CHADS(2), CHA(2)DS(2)-VASc, ATRIA, and Essen scores have been developed for predicting vascular outcomes in stroke patients. We investigated the association between these stroke risk scores and unsuccessful recanalization after endovascular thrombectomy (EVT). Methods: From the natio...

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Detalles Bibliográficos
Autores principales: Kim, Hyung Jun, Park, Moo-Seok, Yoo, Joonsang, Kim, Young Dae, Park, Hyungjong, Kim, Byung Moon, Bang, Oh Young, Kim, Hyeon Chang, Han, Euna, Kim, Dong Joon, Heo, JoonNyung, Choi, Jin Kyo, Lee, Kyung-Yul, Lee, Hye Sun, Shin, Dong Hoon, Choi, Hye-Yeon, Sohn, Sung-Il, Hong, Jeong-Ho, Lee, Jong Yun, Baek, Jang-Hyun, Kim, Gyu Sik, Seo, Woo-Keun, Chung, Jong-Won, Kim, Seo Hyun, Han, Sang Won, Park, Joong Hyun, Kim, Jinkwon, Jung, Yo Han, Cho, Han-Jin, Ahn, Seong Hwan, Lee, Sung Ik, Seo, Kwon-Duk, Chang, Yoonkyung, Song, Tae-Jin, Nam, Hyo Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746082/
https://www.ncbi.nlm.nih.gov/pubmed/35012015
http://dx.doi.org/10.3390/jcm11010274
Descripción
Sumario:Background: The CHADS(2), CHA(2)DS(2)-VASc, ATRIA, and Essen scores have been developed for predicting vascular outcomes in stroke patients. We investigated the association between these stroke risk scores and unsuccessful recanalization after endovascular thrombectomy (EVT). Methods: From the nationwide multicenter registry (Selection Criteria in Endovascular Thrombectomy and Thrombolytic therapy (SECRET)) (Clinicaltrials.gov NCT02964052), we consecutively included 501 patients who underwent EVT. We identified pre-admission stroke risk scores in each included patient. Results: Among 501 patients who underwent EVT, 410 (81.8%) patients achieved successful recanalization (mTICI ≥ 2b). Adjusting for body mass index and p < 0.1 in univariable analysis revealed the association between all stroke risk scores and unsuccessful recanalization (CHADS(2) score: odds ratio (OR) 1.551, 95% confidence interval (CI) 1.198–2.009, p = 0.001; CHA(2)DS(2)VASc score: OR 1.269, 95% CI 1.080–1.492, p = 0.004; ATRIA score: OR 1.089, 95% CI 1.011–1.174, p = 0.024; and Essen score: OR 1.469, 95% CI 1.167–1.849, p = 0.001). The CHADS(2) score had the highest AUC value and differed significantly only from the Essen score (AUC of CHADS(2) score; 0.618, 95% CI 0.554–0.681). Conclusion: All stroke risk scores were associated with unsuccessful recanalization after EVT. Our study suggests that these stroke risk scores could be used to predict recanalization in stroke patients undergoing EVT.