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ICU-Acquired Pneumonia Is Associated with Poor Health Post-COVID-19 Syndrome
Background. Some patients previously presenting with COVID-19 have been reported to develop persistent COVID-19 symptoms. While this information has been adequately recognised and extensively published with respect to non-critically ill patients, less is known about the incidence and factors associa...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746263/ https://www.ncbi.nlm.nih.gov/pubmed/35011967 http://dx.doi.org/10.3390/jcm11010224 |
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author | Martin-Loeches, Ignacio Motos, Anna Menéndez, Rosario Gabarrús, Albert González, Jessica Fernández-Barat, Laia Ceccato, Adrián Pérez-Arnal, Raquel García-Gasulla, Dario Ferrer, Ricard Riera, Jordi Lorente, José Ángel Peñuelas, Óscar Bermejo-Martin, Jesús F. de Gonzalo-Calvo, David Rodríguez, Alejandro Barbé, Ferran Aguilera, Luciano Amaya-Villar, Rosario Barberà, Carme Barberán, José Blandino Ortiz, Aaron Bustamante-Munguira, Elena Caballero, Jesús Carbajales, Cristina Carbonell, Nieves Catalán-González, Mercedes Galbán, Cristóbal Gumucio-Sanguino, Víctor D. de la Torre, Maria del Carmen Díaz, Emili Gallego, Elena García Garmendia, José Luis Garnacho-Montero, José Gómez, José M. Jorge García, Ruth Noemí Loza-Vázquez, Ana Marín-Corral, Judith Martínez de la Gándara, Amalia Martínez Varela, Ignacio Lopez Messa, Juan Albaiceta, Guillermo M. Novo, Mariana Andrea Peñasco, Yhivian Ricart, Pilar Urrelo-Cerrón, Luis Sánchez-Miralles, Angel Sancho Chinesta, Susana Socias, Lorenzo Solé-Violan, Jordi Tamayo Lomas, Luis Vidal, Pablo Torres, Antoni |
author_facet | Martin-Loeches, Ignacio Motos, Anna Menéndez, Rosario Gabarrús, Albert González, Jessica Fernández-Barat, Laia Ceccato, Adrián Pérez-Arnal, Raquel García-Gasulla, Dario Ferrer, Ricard Riera, Jordi Lorente, José Ángel Peñuelas, Óscar Bermejo-Martin, Jesús F. de Gonzalo-Calvo, David Rodríguez, Alejandro Barbé, Ferran Aguilera, Luciano Amaya-Villar, Rosario Barberà, Carme Barberán, José Blandino Ortiz, Aaron Bustamante-Munguira, Elena Caballero, Jesús Carbajales, Cristina Carbonell, Nieves Catalán-González, Mercedes Galbán, Cristóbal Gumucio-Sanguino, Víctor D. de la Torre, Maria del Carmen Díaz, Emili Gallego, Elena García Garmendia, José Luis Garnacho-Montero, José Gómez, José M. Jorge García, Ruth Noemí Loza-Vázquez, Ana Marín-Corral, Judith Martínez de la Gándara, Amalia Martínez Varela, Ignacio Lopez Messa, Juan Albaiceta, Guillermo M. Novo, Mariana Andrea Peñasco, Yhivian Ricart, Pilar Urrelo-Cerrón, Luis Sánchez-Miralles, Angel Sancho Chinesta, Susana Socias, Lorenzo Solé-Violan, Jordi Tamayo Lomas, Luis Vidal, Pablo Torres, Antoni |
author_sort | Martin-Loeches, Ignacio |
collection | PubMed |
description | Background. Some patients previously presenting with COVID-19 have been reported to develop persistent COVID-19 symptoms. While this information has been adequately recognised and extensively published with respect to non-critically ill patients, less is known about the incidence and factors associated with the characteristics of persistent COVID-19. On the other hand, these patients very often have intensive care unit-acquired pneumonia (ICUAP). A second infectious hit after COVID increases the length of ICU stay and mechanical ventilation and could have an influence on poor health post-COVID 19 syndrome in ICU-discharged patients. Methods: This prospective, multicentre, and observational study was carrid out across 40 selected ICUs in Spain. Consecutive patients with COVID-19 requiring ICU admission were recruited and evaluated three months after hospital discharge. Results: A total of 1255 ICU patients were scheduled to be followed up at 3 months; however, the final cohort comprised 991 (78.9%) patients. A total of 315 patients developed ICUAP (97% of them had ventilated ICUAP). Patients requiring invasive mechanical ventilation had more persistent post-COVID-19 symptoms than those who did not require mechanical ventilation. Female sex, duration of ICU stay, development of ICUAP, and ARDS were independent factors for persistent poor health post-COVID-19. Conclusions: Persistent post-COVID-19 symptoms occurred in more than two-thirds of patients. Female sex, duration of ICU stay, development of ICUAP, and ARDS all comprised independent factors for persistent poor health post-COVID-19. Prevention of ICUAP could have beneficial effects in poor health post-COVID-19. |
format | Online Article Text |
id | pubmed-8746263 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87462632022-01-11 ICU-Acquired Pneumonia Is Associated with Poor Health Post-COVID-19 Syndrome Martin-Loeches, Ignacio Motos, Anna Menéndez, Rosario Gabarrús, Albert González, Jessica Fernández-Barat, Laia Ceccato, Adrián Pérez-Arnal, Raquel García-Gasulla, Dario Ferrer, Ricard Riera, Jordi Lorente, José Ángel Peñuelas, Óscar Bermejo-Martin, Jesús F. de Gonzalo-Calvo, David Rodríguez, Alejandro Barbé, Ferran Aguilera, Luciano Amaya-Villar, Rosario Barberà, Carme Barberán, José Blandino Ortiz, Aaron Bustamante-Munguira, Elena Caballero, Jesús Carbajales, Cristina Carbonell, Nieves Catalán-González, Mercedes Galbán, Cristóbal Gumucio-Sanguino, Víctor D. de la Torre, Maria del Carmen Díaz, Emili Gallego, Elena García Garmendia, José Luis Garnacho-Montero, José Gómez, José M. Jorge García, Ruth Noemí Loza-Vázquez, Ana Marín-Corral, Judith Martínez de la Gándara, Amalia Martínez Varela, Ignacio Lopez Messa, Juan Albaiceta, Guillermo M. Novo, Mariana Andrea Peñasco, Yhivian Ricart, Pilar Urrelo-Cerrón, Luis Sánchez-Miralles, Angel Sancho Chinesta, Susana Socias, Lorenzo Solé-Violan, Jordi Tamayo Lomas, Luis Vidal, Pablo Torres, Antoni J Clin Med Article Background. Some patients previously presenting with COVID-19 have been reported to develop persistent COVID-19 symptoms. While this information has been adequately recognised and extensively published with respect to non-critically ill patients, less is known about the incidence and factors associated with the characteristics of persistent COVID-19. On the other hand, these patients very often have intensive care unit-acquired pneumonia (ICUAP). A second infectious hit after COVID increases the length of ICU stay and mechanical ventilation and could have an influence on poor health post-COVID 19 syndrome in ICU-discharged patients. Methods: This prospective, multicentre, and observational study was carrid out across 40 selected ICUs in Spain. Consecutive patients with COVID-19 requiring ICU admission were recruited and evaluated three months after hospital discharge. Results: A total of 1255 ICU patients were scheduled to be followed up at 3 months; however, the final cohort comprised 991 (78.9%) patients. A total of 315 patients developed ICUAP (97% of them had ventilated ICUAP). Patients requiring invasive mechanical ventilation had more persistent post-COVID-19 symptoms than those who did not require mechanical ventilation. Female sex, duration of ICU stay, development of ICUAP, and ARDS were independent factors for persistent poor health post-COVID-19. Conclusions: Persistent post-COVID-19 symptoms occurred in more than two-thirds of patients. Female sex, duration of ICU stay, development of ICUAP, and ARDS all comprised independent factors for persistent poor health post-COVID-19. Prevention of ICUAP could have beneficial effects in poor health post-COVID-19. MDPI 2021-12-31 /pmc/articles/PMC8746263/ /pubmed/35011967 http://dx.doi.org/10.3390/jcm11010224 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Martin-Loeches, Ignacio Motos, Anna Menéndez, Rosario Gabarrús, Albert González, Jessica Fernández-Barat, Laia Ceccato, Adrián Pérez-Arnal, Raquel García-Gasulla, Dario Ferrer, Ricard Riera, Jordi Lorente, José Ángel Peñuelas, Óscar Bermejo-Martin, Jesús F. de Gonzalo-Calvo, David Rodríguez, Alejandro Barbé, Ferran Aguilera, Luciano Amaya-Villar, Rosario Barberà, Carme Barberán, José Blandino Ortiz, Aaron Bustamante-Munguira, Elena Caballero, Jesús Carbajales, Cristina Carbonell, Nieves Catalán-González, Mercedes Galbán, Cristóbal Gumucio-Sanguino, Víctor D. de la Torre, Maria del Carmen Díaz, Emili Gallego, Elena García Garmendia, José Luis Garnacho-Montero, José Gómez, José M. Jorge García, Ruth Noemí Loza-Vázquez, Ana Marín-Corral, Judith Martínez de la Gándara, Amalia Martínez Varela, Ignacio Lopez Messa, Juan Albaiceta, Guillermo M. Novo, Mariana Andrea Peñasco, Yhivian Ricart, Pilar Urrelo-Cerrón, Luis Sánchez-Miralles, Angel Sancho Chinesta, Susana Socias, Lorenzo Solé-Violan, Jordi Tamayo Lomas, Luis Vidal, Pablo Torres, Antoni ICU-Acquired Pneumonia Is Associated with Poor Health Post-COVID-19 Syndrome |
title | ICU-Acquired Pneumonia Is Associated with Poor Health Post-COVID-19 Syndrome |
title_full | ICU-Acquired Pneumonia Is Associated with Poor Health Post-COVID-19 Syndrome |
title_fullStr | ICU-Acquired Pneumonia Is Associated with Poor Health Post-COVID-19 Syndrome |
title_full_unstemmed | ICU-Acquired Pneumonia Is Associated with Poor Health Post-COVID-19 Syndrome |
title_short | ICU-Acquired Pneumonia Is Associated with Poor Health Post-COVID-19 Syndrome |
title_sort | icu-acquired pneumonia is associated with poor health post-covid-19 syndrome |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746263/ https://www.ncbi.nlm.nih.gov/pubmed/35011967 http://dx.doi.org/10.3390/jcm11010224 |
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