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Anti-Inflammatory Activity of a CB2 Selective Cannabinoid Receptor Agonist: Signaling and Cytokines Release in Blood Mononuclear Cells

The endocannabinoid system (ECS) exerts immunosuppressive effects, which are mostly mediated by cannabinoid receptor 2 (CBR2), whose expression on leukocytes is higher than CBR1, mainly localized in the brain. Targeted CBR2 activation could limit inflammation, avoiding CBR1-related psychoactive effe...

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Detalles Bibliográficos
Autores principales:	Capozzi, Antonella, Caissutti, Daniela, Mattei, Vincenzo, Gado, Francesca, Martellucci, Stefano, Longo, Agostina, Recalchi, Serena, Manganelli, Valeria, Riitano, Gloria, Garofalo, Tina, Sorice, Maurizio, Manera, Clementina, Misasi, Roberta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746368/ https://www.ncbi.nlm.nih.gov/pubmed/35011295 http://dx.doi.org/10.3390/molecules27010064

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