Co-Inhibition of P-gp and Hsp90 by an Isatin-Derived Compound Contributes to the Increase of the Chemosensitivity of MCF7/ADR-Resistant Cells to Doxorubicin

Breast cancer is a complex and multi-drug resistant (MDR) disease, which could result in the failure of many chemotherapeutic clinical agents. Discovering effective molecules from natural products or by derivatization from known compounds is the interest of many research studies. The first objective...

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Detalles Bibliográficos
Autores principales: Abdalla, Ashraf N., Di Stefano, Miriana, Poli, Giulio, Tuccinardi, Tiziano, Bader, Ammar, Vassallo, Antonio, Abdallah, Mohamed E., El-Readi, Mahmoud Zaki, Refaat, Bassem, Algarni, Alanood S., Ahmad, Rizwan, Alkahtani, Hamad M., Abdel-Aziz, Alaa A.-M., El-Azab, Adel S., Alqathama, Aljawharah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746493/
https://www.ncbi.nlm.nih.gov/pubmed/35011321
http://dx.doi.org/10.3390/molecules27010090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746493/
https://www.ncbi.nlm.nih.gov/pubmed/35011321
http://dx.doi.org/10.3390/molecules27010090

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