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A Review of Microbial Mediated Iron Nanoparticles (IONPs) and Its Biomedical Applications

Nanotechnology is a booming avenue in science and has a multitude of applications in health, agriculture, and industry. It exploits materials’ size at nanoscale (1–100 nm) known as nanoparticles (NPs). These nanoscale constituents are made via chemical, physical, and biological methods; however, the...

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Autores principales: Nadeem, Muhammad, Khan, Rijma, Shah, Nausheen, Bangash, Ishrat Rehman, Abbasi, Bilal Haider, Hano, Christophe, Liu, Chunzhao, Ullah, Sana, Hashmi, Syed Salman, Nadhman, Akhtar, Celli, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746504/
https://www.ncbi.nlm.nih.gov/pubmed/35010080
http://dx.doi.org/10.3390/nano12010130
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author Nadeem, Muhammad
Khan, Rijma
Shah, Nausheen
Bangash, Ishrat Rehman
Abbasi, Bilal Haider
Hano, Christophe
Liu, Chunzhao
Ullah, Sana
Hashmi, Syed Salman
Nadhman, Akhtar
Celli, Jonathan
author_facet Nadeem, Muhammad
Khan, Rijma
Shah, Nausheen
Bangash, Ishrat Rehman
Abbasi, Bilal Haider
Hano, Christophe
Liu, Chunzhao
Ullah, Sana
Hashmi, Syed Salman
Nadhman, Akhtar
Celli, Jonathan
author_sort Nadeem, Muhammad
collection PubMed
description Nanotechnology is a booming avenue in science and has a multitude of applications in health, agriculture, and industry. It exploits materials’ size at nanoscale (1–100 nm) known as nanoparticles (NPs). These nanoscale constituents are made via chemical, physical, and biological methods; however, the biological approach offers multiple benefits over the other counterparts. This method utilizes various biological resources for synthesis (microbes, plants, and others), which act as a reducing and capping agent. Among these sources, microbes provide an excellent platform for synthesis and have been recently exploited in the synthesis of various metallic NPs, in particular iron. Owing to their biocompatible nature, superparamagnetic properties, small size efficient, permeability, and absorption, they have become an integral part of biomedical research. This review focuses on microbial synthesis of iron oxide nanoparticles using various species of bacteria, fungi, and yeast. Possible applications and challenges that need to be addressed have also been discussed in the review; in particular, their antimicrobial and anticancer potentials are discussed in detail along with possible mechanisms. Moreover, some other possible biomedical applications are also highlighted. Although iron oxide nanoparticles have revolutionized biomedical research, issues such as cytotoxicity and biodegradability are still a major bottleneck in the commercialization of these nanoparticle-based products. Addressing these issues should be the topmost priority so that the biomedical industry can reap maximum benefit from iron oxide nanoparticle-based products.
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spelling pubmed-87465042022-01-11 A Review of Microbial Mediated Iron Nanoparticles (IONPs) and Its Biomedical Applications Nadeem, Muhammad Khan, Rijma Shah, Nausheen Bangash, Ishrat Rehman Abbasi, Bilal Haider Hano, Christophe Liu, Chunzhao Ullah, Sana Hashmi, Syed Salman Nadhman, Akhtar Celli, Jonathan Nanomaterials (Basel) Review Nanotechnology is a booming avenue in science and has a multitude of applications in health, agriculture, and industry. It exploits materials’ size at nanoscale (1–100 nm) known as nanoparticles (NPs). These nanoscale constituents are made via chemical, physical, and biological methods; however, the biological approach offers multiple benefits over the other counterparts. This method utilizes various biological resources for synthesis (microbes, plants, and others), which act as a reducing and capping agent. Among these sources, microbes provide an excellent platform for synthesis and have been recently exploited in the synthesis of various metallic NPs, in particular iron. Owing to their biocompatible nature, superparamagnetic properties, small size efficient, permeability, and absorption, they have become an integral part of biomedical research. This review focuses on microbial synthesis of iron oxide nanoparticles using various species of bacteria, fungi, and yeast. Possible applications and challenges that need to be addressed have also been discussed in the review; in particular, their antimicrobial and anticancer potentials are discussed in detail along with possible mechanisms. Moreover, some other possible biomedical applications are also highlighted. Although iron oxide nanoparticles have revolutionized biomedical research, issues such as cytotoxicity and biodegradability are still a major bottleneck in the commercialization of these nanoparticle-based products. Addressing these issues should be the topmost priority so that the biomedical industry can reap maximum benefit from iron oxide nanoparticle-based products. MDPI 2021-12-31 /pmc/articles/PMC8746504/ /pubmed/35010080 http://dx.doi.org/10.3390/nano12010130 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Nadeem, Muhammad
Khan, Rijma
Shah, Nausheen
Bangash, Ishrat Rehman
Abbasi, Bilal Haider
Hano, Christophe
Liu, Chunzhao
Ullah, Sana
Hashmi, Syed Salman
Nadhman, Akhtar
Celli, Jonathan
A Review of Microbial Mediated Iron Nanoparticles (IONPs) and Its Biomedical Applications
title A Review of Microbial Mediated Iron Nanoparticles (IONPs) and Its Biomedical Applications
title_full A Review of Microbial Mediated Iron Nanoparticles (IONPs) and Its Biomedical Applications
title_fullStr A Review of Microbial Mediated Iron Nanoparticles (IONPs) and Its Biomedical Applications
title_full_unstemmed A Review of Microbial Mediated Iron Nanoparticles (IONPs) and Its Biomedical Applications
title_short A Review of Microbial Mediated Iron Nanoparticles (IONPs) and Its Biomedical Applications
title_sort review of microbial mediated iron nanoparticles (ionps) and its biomedical applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746504/
https://www.ncbi.nlm.nih.gov/pubmed/35010080
http://dx.doi.org/10.3390/nano12010130
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