Design and Synthesis of New Thiophene/Thieno[2,3-d]pyrimidines along with Their Cytotoxic Biological Evaluation as Tyrosine Kinase Inhibitors in Addition to Their Apoptotic and Autophagic Induction

This work describes the synthesis and anticancer activity against kinase enzymes of newly designed thiophene and thieno[2,3-d]pyrimidine derivatives, along with their potential to activate autophagic and apoptotic cell death in cancer cells. The designed compounds were scanned for their affinity for...

Descripción completa

Detalles Bibliográficos
Autores principales: Elmongy, Elshaymaa I., Attallah, Nashwah G. M., Altwaijry, Najla, AlKahtani, Manal Mubarak, Henidi, Hanan Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746632/
https://www.ncbi.nlm.nih.gov/pubmed/35011354
http://dx.doi.org/10.3390/molecules27010123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746632/
https://www.ncbi.nlm.nih.gov/pubmed/35011354
http://dx.doi.org/10.3390/molecules27010123

Ejemplares similares