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The Effects of Deworming and Multiple Micronutrients on Anaemia in Preschool Children in Bangladesh: Analysis of Five Cross-Sectional Surveys

Anaemia is a major public health problem among children < 5 years of age in Bangladesh due to recurrent intestinal parasite infections. The aim of this study was to understand the association between combining deworming and MNP home fortification (MNP + Deworming) and the prevalence of anaemia am...

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Autores principales: Sarma, Haribondhu, Wangdi, Kinley, Tariqujjaman, Md, Das, Ratish, Rahman, Mahfuzur, Kelly, Matthew, Ahmed, Tahmeed, Gray, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746749/
https://www.ncbi.nlm.nih.gov/pubmed/35011023
http://dx.doi.org/10.3390/nu14010150
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author Sarma, Haribondhu
Wangdi, Kinley
Tariqujjaman, Md
Das, Ratish
Rahman, Mahfuzur
Kelly, Matthew
Ahmed, Tahmeed
Gray, Darren J.
author_facet Sarma, Haribondhu
Wangdi, Kinley
Tariqujjaman, Md
Das, Ratish
Rahman, Mahfuzur
Kelly, Matthew
Ahmed, Tahmeed
Gray, Darren J.
author_sort Sarma, Haribondhu
collection PubMed
description Anaemia is a major public health problem among children < 5 years of age in Bangladesh due to recurrent intestinal parasite infections. The aim of this study was to understand the association between combining deworming and MNP home fortification (MNP + Deworming) and the prevalence of anaemia among children < 5 years of age in Bangladesh. We used pooled data from five cross-sectional surveys and performed multivariable logistic regression and calculated crude and adjusted odds ratios (AORs) to quantify the association of anaemia with the exposure variables. A total of 9948 households were considered for this paper. In the unadjusted logistic regression, no significant association was detected between the effective MNP coverage and anaemia prevalence, but the associations were significant (p < 0.001) between the deworming and anaemia prevalence and between the MNP + Deworming condition and anaemia prevalence. In the adjusted model, children who were exposed to both deworming and effective MNP coverage were 30% (AOR 0.70; 95% CI 0.52, 0.94; p = 0.018) less likely to be anaemic compared with children who were unexposed to combined MNP + Deworming. The combined effects of deworming and MNP supplementation on the reduction in anaemia prevalence highlighted the importance of using integrated and multidisciplinary intervention strategies.
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spelling pubmed-87467492022-01-11 The Effects of Deworming and Multiple Micronutrients on Anaemia in Preschool Children in Bangladesh: Analysis of Five Cross-Sectional Surveys Sarma, Haribondhu Wangdi, Kinley Tariqujjaman, Md Das, Ratish Rahman, Mahfuzur Kelly, Matthew Ahmed, Tahmeed Gray, Darren J. Nutrients Article Anaemia is a major public health problem among children < 5 years of age in Bangladesh due to recurrent intestinal parasite infections. The aim of this study was to understand the association between combining deworming and MNP home fortification (MNP + Deworming) and the prevalence of anaemia among children < 5 years of age in Bangladesh. We used pooled data from five cross-sectional surveys and performed multivariable logistic regression and calculated crude and adjusted odds ratios (AORs) to quantify the association of anaemia with the exposure variables. A total of 9948 households were considered for this paper. In the unadjusted logistic regression, no significant association was detected between the effective MNP coverage and anaemia prevalence, but the associations were significant (p < 0.001) between the deworming and anaemia prevalence and between the MNP + Deworming condition and anaemia prevalence. In the adjusted model, children who were exposed to both deworming and effective MNP coverage were 30% (AOR 0.70; 95% CI 0.52, 0.94; p = 0.018) less likely to be anaemic compared with children who were unexposed to combined MNP + Deworming. The combined effects of deworming and MNP supplementation on the reduction in anaemia prevalence highlighted the importance of using integrated and multidisciplinary intervention strategies. MDPI 2021-12-29 /pmc/articles/PMC8746749/ /pubmed/35011023 http://dx.doi.org/10.3390/nu14010150 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sarma, Haribondhu
Wangdi, Kinley
Tariqujjaman, Md
Das, Ratish
Rahman, Mahfuzur
Kelly, Matthew
Ahmed, Tahmeed
Gray, Darren J.
The Effects of Deworming and Multiple Micronutrients on Anaemia in Preschool Children in Bangladesh: Analysis of Five Cross-Sectional Surveys
title The Effects of Deworming and Multiple Micronutrients on Anaemia in Preschool Children in Bangladesh: Analysis of Five Cross-Sectional Surveys
title_full The Effects of Deworming and Multiple Micronutrients on Anaemia in Preschool Children in Bangladesh: Analysis of Five Cross-Sectional Surveys
title_fullStr The Effects of Deworming and Multiple Micronutrients on Anaemia in Preschool Children in Bangladesh: Analysis of Five Cross-Sectional Surveys
title_full_unstemmed The Effects of Deworming and Multiple Micronutrients on Anaemia in Preschool Children in Bangladesh: Analysis of Five Cross-Sectional Surveys
title_short The Effects of Deworming and Multiple Micronutrients on Anaemia in Preschool Children in Bangladesh: Analysis of Five Cross-Sectional Surveys
title_sort effects of deworming and multiple micronutrients on anaemia in preschool children in bangladesh: analysis of five cross-sectional surveys
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746749/
https://www.ncbi.nlm.nih.gov/pubmed/35011023
http://dx.doi.org/10.3390/nu14010150
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