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Excess Folic Acid Supplementation before and during Pregnancy and Lactation Alters Behaviors and Brain Gene Expression in Female Mouse Offspring

Use of folic acid (FA) during early pregnancy protects against birth defects. However, excess FA has shown gender-specific neurodevelopmental toxicity. Previously, we fed the mice with 2.5 times the recommended amount of FA one week prior to mating and during the pregnancy and lactation periods, and...

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Detalles Bibliográficos
Autores principales: Yang, Xingyue, Sun, Wenyan, Wu, Qian, Lin, Hongyan, Lu, Zhixing, Shen, Xin, Chen, Yongqi, Zhou, Yan, Huang, Li, Wu, Feng, Liu, Fei, Chu, Dandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746785/
https://www.ncbi.nlm.nih.gov/pubmed/35010941
http://dx.doi.org/10.3390/nu14010066