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Excess Folic Acid Supplementation before and during Pregnancy and Lactation Alters Behaviors and Brain Gene Expression in Female Mouse Offspring
Use of folic acid (FA) during early pregnancy protects against birth defects. However, excess FA has shown gender-specific neurodevelopmental toxicity. Previously, we fed the mice with 2.5 times the recommended amount of FA one week prior to mating and during the pregnancy and lactation periods, and...
Autores principales: | Yang, Xingyue, Sun, Wenyan, Wu, Qian, Lin, Hongyan, Lu, Zhixing, Shen, Xin, Chen, Yongqi, Zhou, Yan, Huang, Li, Wu, Feng, Liu, Fei, Chu, Dandan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746785/ https://www.ncbi.nlm.nih.gov/pubmed/35010941 http://dx.doi.org/10.3390/nu14010066 |
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