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Copper(II) Phenanthroline-Based Complexes as Potential AntiCancer Drugs: A Walkthrough on the Mechanisms of Action
Copper is an endogenous metal ion that has been studied to prepare a new antitumoral agent with less side-effects. Copper is involved as a cofactor in several enzymes, in ROS production, in the promotion of tumor progression, metastasis, and angiogenesis, and has been found at high levels in serum a...
Autores principales: | Masuri, Sebastiano, Vaňhara, Petr, Cabiddu, Maria Grazia, Moráň, Lukáš, Havel, Josef, Cadoni, Enzo, Pivetta, Tiziana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746828/ https://www.ncbi.nlm.nih.gov/pubmed/35011273 http://dx.doi.org/10.3390/molecules27010049 |
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