Paraneoplastic Cerebellar Syndrome Presented as Cerebellar Hypermetabolism in a Patient With Occult Breast Carcinoma

A 47-year-old woman presented with an acute cerebellar syndrome. Neither cerebellar atrophy nor an infarction or tumor was shown on MRI. A diagnostic CT demonstrated enlarged axillary lymph nodes, but no primary tumor. Puncture of these nodes showed non–small cell carcinoma. (18)F-FDG PET/CT imaging...

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Autores principales: Booij, Jan, Adam, Judit A., van Eerde, Maaike S., Bronner, Irene M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Interesting Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746891/
https://www.ncbi.nlm.nih.gov/pubmed/35006107
http://dx.doi.org/10.1097/RLU.0000000000004016
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author Booij, Jan
Adam, Judit A.
van Eerde, Maaike S.
Bronner, Irene M.
author_facet Booij, Jan
Adam, Judit A.
van Eerde, Maaike S.
Bronner, Irene M.
author_sort Booij, Jan
collection PubMed
description A 47-year-old woman presented with an acute cerebellar syndrome. Neither cerebellar atrophy nor an infarction or tumor was shown on MRI. A diagnostic CT demonstrated enlarged axillary lymph nodes, but no primary tumor. Puncture of these nodes showed non–small cell carcinoma. (18)F-FDG PET/CT imaging was performed and suggested an occult breast carcinoma, which was confirmed by pathological examination. It also showed cerebellar hypermetabolism, consistent with a PCS (paraneoplastic cerebellar syndrome). This case shows that (18)F-FDG PET imaging may be of value in patients in which a PCS is considered clinically, particularly in patients suspicious for an occult malignancy.
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spelling pubmed-87468912022-01-14 Paraneoplastic Cerebellar Syndrome Presented as Cerebellar Hypermetabolism in a Patient With Occult Breast Carcinoma Booij, Jan Adam, Judit A. van Eerde, Maaike S. Bronner, Irene M. Clin Nucl Med Interesting Images A 47-year-old woman presented with an acute cerebellar syndrome. Neither cerebellar atrophy nor an infarction or tumor was shown on MRI. A diagnostic CT demonstrated enlarged axillary lymph nodes, but no primary tumor. Puncture of these nodes showed non–small cell carcinoma. (18)F-FDG PET/CT imaging was performed and suggested an occult breast carcinoma, which was confirmed by pathological examination. It also showed cerebellar hypermetabolism, consistent with a PCS (paraneoplastic cerebellar syndrome). This case shows that (18)F-FDG PET imaging may be of value in patients in which a PCS is considered clinically, particularly in patients suspicious for an occult malignancy. Lippincott Williams & Wilkins 2022-02 2022-01-07 /pmc/articles/PMC8746891/ /pubmed/35006107 http://dx.doi.org/10.1097/RLU.0000000000004016 Text en Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Interesting Images
Booij, Jan
Adam, Judit A.
van Eerde, Maaike S.
Bronner, Irene M.
Paraneoplastic Cerebellar Syndrome Presented as Cerebellar Hypermetabolism in a Patient With Occult Breast Carcinoma
title Paraneoplastic Cerebellar Syndrome Presented as Cerebellar Hypermetabolism in a Patient With Occult Breast Carcinoma
title_full Paraneoplastic Cerebellar Syndrome Presented as Cerebellar Hypermetabolism in a Patient With Occult Breast Carcinoma
title_fullStr Paraneoplastic Cerebellar Syndrome Presented as Cerebellar Hypermetabolism in a Patient With Occult Breast Carcinoma
title_full_unstemmed Paraneoplastic Cerebellar Syndrome Presented as Cerebellar Hypermetabolism in a Patient With Occult Breast Carcinoma
title_short Paraneoplastic Cerebellar Syndrome Presented as Cerebellar Hypermetabolism in a Patient With Occult Breast Carcinoma
title_sort paraneoplastic cerebellar syndrome presented as cerebellar hypermetabolism in a patient with occult breast carcinoma
topic Interesting Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746891/
https://www.ncbi.nlm.nih.gov/pubmed/35006107
http://dx.doi.org/10.1097/RLU.0000000000004016
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