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Roles of the CXCL8-CXCR1/2 Axis in the Tumor Microenvironment and Immunotherapy
In humans, Interleukin-8 (IL-8 or CXCL8) is a granulocytic chemokine with multiple roles within the tumor microenvironment (TME), such as recruiting immunosuppressive cells to the tumor, increasing tumor angiogenesis, and promoting epithelial-to-mesenchymal transition (EMT). All of these effects of...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746913/ https://www.ncbi.nlm.nih.gov/pubmed/35011369 http://dx.doi.org/10.3390/molecules27010137 |